Skeletal Muscle Relaxants-9 Flashcards

1
Q

Biologic drug

A

A substance made from a living organism or its products used to prevent or treat disease

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2
Q

Black box warning (boxed warning)

A

A warning that appears in the instructions for use surrounded by a thick black box to alert medical professionals to serious or life-threatening adverse effects associated with the drug usage

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3
Q

Blepharospasm

A

Involuntary blinking or spasm of the eyelid

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4
Q

Botulism

A

 A life-threatening illness caused by the bacteria clostridium botulinum

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5
Q

Centrally acting skeletal muscle relaxant

A

drug that inhibits the skeletal muscle contraction by blocking conduction within the spinal cord

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6
Q

Depolarizing blocker

A

Produces paralysis by first causing nerve transmission, followed by inhibition of nerve transmission

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7
Q

Dysphagia

A

Difficulty swallowing

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8
Q

Dysphonia

A

Difficulty speaking due to a physical disorder with the mouth, tongue, throat, or vocal cords

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9
Q

Dystonia

A

 A movement disorder in which muscles contract and spasm involuntarily

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10
Q

Fasciculation

A

Twitchings of muscle fiber groups

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11
Q

Hyperhidrosis

A

Condition of excessive sweating

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12
Q

Hyperthermia

A

 abnormally high body temperature

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13
Q

Incompatibility

A

undesirable interaction of drugs not suitable for combination or administration together

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14
Q

Intrathecal

A

Space around the brain and spinal cord that contains the cerebrospinal fluid

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15
Q

Malignant hyperthermia

A

 condition and susceptible individuals resulting in a life-threatening elevation in body temperature

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16
Q

Mitochondria

A

Normal structures responsible for energy production in cells

17
Q

Myelin

A

The fatty substance that covers and protects nerves and allows efficient conduction of action potentials down the axon

18
Q

Myofilaments

A

Minute fibers located throughout the cytoplasm of cells, composed of the protein Acton, that maintain the structural integrity of the cell

19
Q

Neuromuscular junction NMJ

A

Area where the motor neuron axon terminals meets the muscle tissue

20
Q

Neurotoxin

A

A substance that is destructive to nerve tissue

21
Q

Nicotinic muscle receptor

A

Cholinergic receptor located at the neuromuscular junction of skeletal muscle

22
Q

Nondepolarizing blocker

A

Produces paralysis by inhibiting nerve transmission

23
Q

Peripheral skeletal muscle relaxant

A

drug that inhibits muscle contraction at the neuromuscular junction or within the contractile process

24
Q

Potentiates

A

Produces an action that is greater than either of the components can produce alone; synergy

25
Sarcolemma
A thin membrane enclosing a striated (skeletal) muscle fiber
26
Sarcoplasm
The cytoplasm of a striated (skeletal) muscle fiber
27
Sarcoplasmic reticulum
Specialized organelle in the muscle cell that releases calcium ions during muscle contraction and absorbs calcium ions during relaxation
28
Schwann cell
 any cell that covers the axons in the peripheral nervous system and forms to myelin sheath
29
Spasmolytics
Drugs that relieve, interrupt, or prevent muscle spasms (intermittent muscle contractions often associated with pain)
30
Spread effect
Condition in which the intramuscularly injected substance moves out of the area of administration and produces an effect on other tissues
31
Strabismus
Condition in which the eyes are not aligned in point in different directions, cross-eyed
32
Synaptic cleft
Space (synapse)between a motor nerve ending in a skeletal muscle membrane that contains acetylcholine ACH receptors
33
Synaptic knob
Contains vesicles the store and release neurotransmitters
34
Synaptic vesicles
A small membrane-bound structure in the axon terminals of nerve cells that contains neurotransmitters and releases them when an action potential reaches the terminal
35
Vagolytic action
Inhibition of the vagus nerve to the heart, causing the heart rate to increase (counteraction to vagal tone that causes bradycardia)
36
Vasodilator
Substance that relaxes the muscles (sphincters) controlling blood vessels, leading to increased blood flow