Skeletal Muscle Relaxants-9 Flashcards
Biologic drug
A substance made from a living organism or its products used to prevent or treat disease
Black box warning (boxed warning)
A warning that appears in the instructions for use surrounded by a thick black box to alert medical professionals to serious or life-threatening adverse effects associated with the drug usage
Blepharospasm
Involuntary blinking or spasm of the eyelid
Botulism
 A life-threatening illness caused by the bacteria clostridium botulinum
Centrally acting skeletal muscle relaxant
drug that inhibits the skeletal muscle contraction by blocking conduction within the spinal cord
Depolarizing blocker
Produces paralysis by first causing nerve transmission, followed by inhibition of nerve transmission
Dysphagia
Difficulty swallowing
Dysphonia
Difficulty speaking due to a physical disorder with the mouth, tongue, throat, or vocal cords
Dystonia
 A movement disorder in which muscles contract and spasm involuntarily
Fasciculation
Twitchings of muscle fiber groups
Hyperhidrosis
Condition of excessive sweating
Hyperthermia
 abnormally high body temperature
Incompatibility
undesirable interaction of drugs not suitable for combination or administration together
Intrathecal
Space around the brain and spinal cord that contains the cerebrospinal fluid
Malignant hyperthermia
 condition and susceptible individuals resulting in a life-threatening elevation in body temperature
Mitochondria
Normal structures responsible for energy production in cells
Myelin
The fatty substance that covers and protects nerves and allows efficient conduction of action potentials down the axon
Myofilaments
Minute fibers located throughout the cytoplasm of cells, composed of the protein Acton, that maintain the structural integrity of the cell
Neuromuscular junction NMJ
Area where the motor neuron axon terminals meets the muscle tissue
Neurotoxin
A substance that is destructive to nerve tissue
Nicotinic muscle receptor
Cholinergic receptor located at the neuromuscular junction of skeletal muscle
Nondepolarizing blocker
Produces paralysis by inhibiting nerve transmission
Peripheral skeletal muscle relaxant
drug that inhibits muscle contraction at the neuromuscular junction or within the contractile process
Potentiates
Produces an action that is greater than either of the components can produce alone; synergy