Intro -1 Flashcards

1
Q

Adverse effect

A

General term for undesirable and potentially harmful drug effect

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2
Q

Agonist

A

Drug that binds to a receptor and activates a physiologic response or drug action

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3
Q

Antagonist

A

Drug that binds to a receptor and interferes with other drugs or substances from producing a drug effect

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4
Q

Chemical name

A

Name that defined the chemical composition of a drug

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5
Q

Contraindications

A

Situation or conditions when a certain drug should not be administered

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6
Q

Controlled substance

A

Drug that has the potential for abuse and thus is regulated by law

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7
Q

Dose

A

A measurement of the amount of drug that is administered

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8
Q

Drug

A

Chemical substance that produces a change in body function

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9
Q

Drug indications

A

Intended or indicated uses for any drug

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10
Q

ED50

A

Effective dose 50 or dose that will produce an effect that is half of the maximal response

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11
Q

Generic name

A

Non-proprietary name of a drug

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12
Q

LD50

A

Lethal dose 50 or dose that will kill 50% of the laboratory animals tested

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13
Q

Mechanism of action

A

Explanation of how a drug produces it’s effects

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14
Q

Non-prescription over the counter OTC drug

A

Drug that can be purchased without the services of a physician

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15
Q

Pharmacology

A

Study of drugs

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16
Q

Potency

A

Measure of the strength or concentration of a drug required to produce a specific effect

17
Q

Prescription drug

A

Drug for which dispensing requires a written or phone order that can only be issued by or under the direction of a licensed physician

18
Q

Receptor

A

Specific cellular structure that a drug binds to in order to produce a physiological effect

19
Q

Side effect

A

Drug effect other than the therapeutic affect that is usually undesirable but not harmful

20
Q

Site of action

A

Location within the body where a drug exerts its therapeutic effect often a specific drug receptor

21
Q

Therapeutic effect

A

Desire drug affect to alleviate some condition or symptoms of disease

22
Q

Therapeutic index TI

A

Ratio of the LD50 to the ED50 in animal studies

23
Q

Toxic effect

A

Undesirable drug effect that implies drug poisoning can be very harmful or life-threatening

24
Q

Trade name

A

Patented proprietary name of a drug sold by a specific drug manufacturer also referred to as the brand name

25
Q

Competitive antagonism

A

Compete for same receptor

26
Q

Uncompetitive antagonism

A

Interference without binding to the same receptors

27
Q

Dose response relationship

A

Response depends on amount of drug given

28
Q

Dose response curve

A

When does response relationship is plotted on a graph

29
Q

Ceiling effect

A

Limit of some drug classes to produce a particular effect. Above a certain dosage no further increase in effect is observed

30
Q

USP/NF

A

United States Pharmacopeia/national formulary