Intro -1 Flashcards

1
Q

Adverse effect

A

General term for undesirable and potentially harmful drug effect

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2
Q

Agonist

A

Drug that binds to a receptor and activates a physiologic response or drug action

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3
Q

Antagonist

A

Drug that binds to a receptor and interferes with other drugs or substances from producing a drug effect

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4
Q

Chemical name

A

Name that defined the chemical composition of a drug

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5
Q

Contraindications

A

Situation or conditions when a certain drug should not be administered

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6
Q

Controlled substance

A

Drug that has the potential for abuse and thus is regulated by law

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7
Q

Dose

A

A measurement of the amount of drug that is administered

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8
Q

Drug

A

Chemical substance that produces a change in body function

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9
Q

Drug indications

A

Intended or indicated uses for any drug

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10
Q

ED50

A

Effective dose 50 or dose that will produce an effect that is half of the maximal response

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11
Q

Generic name

A

Non-proprietary name of a drug

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12
Q

LD50

A

Lethal dose 50 or dose that will kill 50% of the laboratory animals tested

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13
Q

Mechanism of action

A

Explanation of how a drug produces it’s effects

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14
Q

Non-prescription over the counter OTC drug

A

Drug that can be purchased without the services of a physician

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15
Q

Pharmacology

A

Study of drugs

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16
Q

Potency

A

Measure of the strength or concentration of a drug required to produce a specific effect

17
Q

Prescription drug

A

Drug for which dispensing requires a written or phone order that can only be issued by or under the direction of a licensed physician

18
Q

Receptor

A

Specific cellular structure that a drug binds to in order to produce a physiological effect

19
Q

Side effect

A

Drug effect other than the therapeutic affect that is usually undesirable but not harmful

20
Q

Site of action

A

Location within the body where a drug exerts its therapeutic effect often a specific drug receptor

21
Q

Therapeutic effect

A

Desire drug affect to alleviate some condition or symptoms of disease

22
Q

Therapeutic index TI

A

Ratio of the LD50 to the ED50 in animal studies

23
Q

Toxic effect

A

Undesirable drug effect that implies drug poisoning can be very harmful or life-threatening

24
Q

Trade name

A

Patented proprietary name of a drug sold by a specific drug manufacturer also referred to as the brand name

25
Competitive antagonism
Compete for same receptor
26
Uncompetitive antagonism
Interference without binding to the same receptors
27
Dose response relationship
Response depends on amount of drug given
28
Dose response curve
When does response relationship is plotted on a graph
29
Ceiling effect
Limit of some drug classes to produce a particular effect. Above a certain dosage no further increase in effect is observed
30
USP/NF
United States Pharmacopeia/national formulary