Pharmacokinetics -2

Question 1

Bioavailability

Answer 1

Percentage of the drug dosage that is absorbed

Question 2

Drug absorption

Answer 2

Entrance of a drug into the bloodstream from its site of administration

Question 3

Drug addiction

Answer 3

Condition of drug abuse and drug dependence that is characterized by compulsive drug behavior

Question 4

Drug distribution

Answer 4

Passage of a drug from the blood to the tissues and organs of the body

Question 5

Drug excretion

Answer 5

Elimination of the drug from the body

Question 6

Drug metabolism

Answer 6

The enzymatic biotransformation of a drug into metabolites

Question 7

Drug microsomal metabolizing system DMMS

Answer 7

Group of enzymes located primarily in the liver that function to metabolize (biotransformation) drugs

Question 8

Drug tolerance

Answer 8

Decrease drug affect occurring after repeated drug administration

Question 9

Enzyme induction

Answer 9

Increase in the amount of drug metabolizing enzymes after repeated administration of certain drugs

Question 10

Enzyme inhibition

Answer 10

Inhibition of drug metabolizing enzymes by certain drugs

Question 11

First pass metabolism

Answer 11

Drug metabolism that occurs in the intestines and liver during oral absorption of drugs into the systemic circulation

Question 12

Half life

Answer 12

Time required for the body to reduce the amount of drug in the plasma by 1/2

Question 13

Individual variation

Answer 13

Difference in the effects of drugs and drug dosages from one person to another

Question 14

Intramuscular (IM) injection

Answer 14

Route of drug administration; drug is injected into gluteal or deltoid muscles

Question 15

Intravenous IV injection

Answer 15

Route of drug administration; drug is injected directly into a vein

Question 16

Loading dose

Answer 16

Initial drug dose administered to rapidly achieve therapeutic drug concentrations

Question 17

Maintenance dose

Answer 17

Those administered to maintain drug levels in blood in the therapeutic range

Question 18

Oral administration

Answer 18

Route of drug in ministration by way of the mouth through swallowing

Question 19

Paraenteral administration

Answer 19

Route of drug administration that does not involve the gastrointestinal G.I. tract

Question 20

Pharmacokinetics

Answer 20

Describe the processes of drug absorption drug distribution drug metabolism and drug excretion