SIHD & Angina - Presentation Flashcards

1
Q

What is stable angina?

A

Constricting chest pain with or without radiation to left arm/jaw. Stable when it is relived with GTN or rest.

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2
Q

Outline the pathophysiology of angina.

A
  • mismatch between O2 supply/demand to myocardium
  • main cause is atheroma in the coronary arteries
  • less commonly: artery spasm, arteritis
  • myocardial ischaemia leads to symptoms of angina
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3
Q

What are some precipitants of angina?

4

A
  • exercise
  • cold weather
  • emotional stress
  • heavy meal
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4
Q

Stable angina becomes symptomatic usually when obstructive plaque (atheroma) obstructs ____ of the artery lumen.

A

> 70%

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5
Q

What important things should be asked in a patient Hx?

5

A
  • site of pain (retrosternal)
  • radiation (arm, jaw)
  • characteristic (tight band, pressure, heaviness)
  • exacerbating factors (GTN, rest)
  • aggravating factors (exercise)
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6
Q

What features point to something other than angina?

4

A
  • sharp/stabbing pain (pleuritic, pericardial)
  • very localised, pin point
  • no pattern to pain (rest)
  • onset (not after exercise)
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7
Q

Outline some differential diagnosis for different systems.

A

CVS: aortic dissection, pericarditis

Resp: pleurisy, pneumonia

MSK: costochondritis

GI: reflux, peptic ulceration

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8
Q

In what patients might myocardial ischaemia result in symptoms other than chest pain/angina?

A

diabetics/elderly

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9
Q

Outline non-modifiable risk factors.

4

A

Age
gender
family history
genetic factors

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10
Q

Outline modifiable risk factors.

5

A
  • Smoking
  • Lifestyle - exercise & diet
  • Diabetes mellitus (glycaemic control reduces CV risk)
  • Hypertension (BP control reduces CV risk)
  • Hyperlipidaemia (lowering reduces CV risk)
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11
Q

What are clinical signs of stable angina?

6

A
  • Tar stains on fingers
  • Obesity (centripedal)
  • Xanthalasma and corneal arcus (hypercholesterolaemia)
  • Hypertension
  • Abdominal aortic aneurysm arterial bruits, absent or reduced peripheral pulses.
  • Diabetic retinopathy, hypertensive retinopathy on fundoscopy.
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12
Q

What are some signs of exacerbating or associated conditions?

5

A
  • Pallor of anaemia
  • Tachycardia, tremor, hyper-reflexia of hyperthyroidism
  • Ejection systolic murmur, plateau pulse of aortic stenosis
  • Pansystolic murmur of MR
  • Signs of heart failure such as basal crackles, elevated JVP, peripheral oedema.
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13
Q

What investigations aid in diagnosing angina?

4

A
  • Hx/exam
  • Bloods
  • CXR
  • ECG (+/- ETT)
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14
Q

What blood tests would be carried out?

A
FBC
UEs
lipid profile
HbA1c/fasting glucose
LFTs
TFT
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15
Q

What would a CXR help rule out or identify?

A

pulmonary oedema

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16
Q

What might be picked up on an ECG?

2

hint: ACS

A
  • pathological Q-waves (previous MI)

- lateral ST depression (LVH)

17
Q

What is considered the gold standard diagnostic investigation?

A

CT coronary angiography

18
Q

OutliSne medical therapy for stable angina.

A

Immediate relief:

  • GTN spray
  • K+ blockers

Long term relief:

  • B-blocker
  • CCB
  • long-acting nitrites (e.g. ivabradine)

Secondary prevention (AAAA)

  • atorvostatin
  • aspirin
  • ACEi
  • a B-blocker
19
Q

What does a statin do?

A

Reduce LDL-cholesterol deposition in atheroma and also stabilise atheroma reducing plaque rupture and ACS.

20
Q

What are the surgical treatment strategies?

A
  • Percutaneous coronary intervention (PCI)

- CABG