Shingles-Reactivation of the varicella-zoster virus (VZV) Flashcards

1
Q

What is shingles due to?

A

Reactivation of the varicella zoster virus in the dorsal root ganglia

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2
Q

How does shingles tend to distribute?

A

Dermatomal distribution

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3
Q

What are the most commonly affected dermatomes?

A

T1-L2

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4
Q

How can shingles present?

A

Tingling feeling in a dermatomal distribution
Progresses to erythematous papules occurring along one or more dermatomes within a few days
Erythematous papules develop into fluid-filled vesicles which then crust over and heal.

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5
Q

What happens to the erthematous papules in someone with shingles?

A

Becomes vesicular and then crusts over

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6
Q

How is the rash described in someone with shingles?

A

Well demarcated erythematous rash that becomes vesicular
Doesn’t cross the midline

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7
Q

What other symptoms can shingles present with?

A

Flu like symptoms
fever, headache, malaise

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8
Q

What can occur if shingles affects the trigeminal nerve?

A

Eye is affected- corneal ulcers

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9
Q

How is shingles diagnosed?

A

Clinically

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10
Q

What is the most common complication of shingles?

A

Post-herpetic neuralgia

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11
Q

What is the most common complication of shingles?

A

Post-herpetic neuralgia

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12
Q

What is post-herpetic neuralgia?

A

Pain occurring at site of healed shingles infection
Can cause neuropathic type pain- burning, pins and needles
Can cause allodynia

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13
Q

Is shingles contagious?

A

Yes

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14
Q

Who does someone with shingles need to avoid?

A

Immunocompromised
Pregnant

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15
Q

How long is someone with shingles infectious?

A

Until all the lesions have crusted over- usualy 5-7 days

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16
Q

What is usually the first line medical management of someone with shingles?

A

Paracetamol
NSAIDs

17
Q

What might you consider giving in teh first 2 weeks to an immunocompetent adults with localized shingles if the pain is severe and not responding to the above treatments?

A

oral corticosteroids

18
Q

When is it recommneded to give antivirals for shingles?

A

Within 72 hours

19
Q

What is the advantage of giving antivirals for shingles?

A

Reduce the risk of post herpetic neuralgia

20
Q

What are examples of antivirals taht can be given for shingles?

A

Aciclovir
Famciclovir
Valaciclovir