Infectious Mononucleosis Flashcards
What is another term for infectious mononucleosis?
Glandular fever
What is infectious mononucleosis the most common manifestation of?
EBV virus
What does EBV stand for?
Epstein-Barr virus
What is the classic triad of glandular fever?
Sore throat
Pyrexia
Lymphadenopathy
Which lymph nodes tend to be enlarged?
Lymph nodes in anterior and posterior triangles of the neck
How does the lymphadenopathy in infectious mononucleosis differ to that in tonsilitis?
Tonsillitis which typically only results in the upper anterior cervical chain being enlarged
What are the other possible symptoms of infectious mononucleosis?
palatal petechiae
splenomegaly
hepatitis, transient rise in ALT
lymphocytosis
haemolytic anaemia secondary to cold agglutins (IgM)
a maculopapular, pruritic rash
When does a maculopapular pruritic rash tend to develop in people with infectious mononucleosis?
It develops in patients who take ampicillin/amoxicillin whilst they have infectious mononucleosis
When do the symptoms of infectious mononucleosis tend to resolve?
After 2-4 weeks.
How is infectious monnucleosis diagnosed?
Monospot test- heterophil antibody test
When should the monospot test be carried out?
In the 2nd week of the illness to confirm a diagnosis
What other tests can be carried out in someone with suspected infetious mononucleosis?
FBC -raised lymphocytes
EBV viral serology
What would you see on a FBC of someone with infectious mononucleosis?
Lymphocytosis
When would you consider EBV serology?
Under 12
Immunocompromised
Monospot remains negative but clinical suspicion is high.
What is the main management of infectious mononucleosis?
Conservative management- fluid and analgesia
