Shigella sp. Flashcards

1
Q

Etiologia

A

-Aerobios facultativos
-Bastonetes Gram-negativos
-Nao formam esporos
-imoveis

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2
Q

Transmissao

A

Via fecal ora.

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3
Q

Sinonimia

A

Disenteria bacilar classica

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4
Q

E dividida em 4 especies:

A

S. dysenteriae
S. flexneri
S.boydii
S.sonnei

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5
Q

Qual especie e a causa mais comum de shigelose no mundo (60%)

A

S.flexneri

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6
Q

A entrada no epitelio do colon e mediada de duas maneiras:

A

Ruffling (ondulacao) da membrana das celulas M e desestabilizacao da barreira epitelial.

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7
Q

A destruicao da barreia epitelial e mediada por:

A

Por citocinas pro-inflamatorias e quimiotaxicas

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8
Q

O organismo produz…

A

Produz shigatoxina, uma exotoxina q inibe a sintese proteica semlhante a da colera

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9
Q

Periodo de incubacao

A

16-72 h

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10
Q

Mecanismos fisiopatologicos

A

Producao de toxina e/ou invasao tecidual

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