Sheehan's syndrome

Question 1

What is Sheehan’s syndrome

Answer 1

rare complication ofpost-partum haemorrhage, where the drop in circulating blood volume leads toavascular necrosisof thepituitary gland

Question 2

What is the most affected region in Sheehan’s syndrome

Answer 2

Anterior pituitary gland

Question 3

What system provides blood to the anterior pituitary

Answer 3

hypothalamo-hypophyseal portal system

Question 4

Presentation of Sheehan’s syndrome

Answer 4

• Reduced lactation(lack of prolactin)
• Amenorrhea(lack of LH and FSH)
• Adrenal insufficiencyandadrenal crisis, caused bylow cortisol(lack of ACTH)
• Hypothyroidismwithlow thyroid hormones(lack of TSH)

Question 5

Management of Sheehan’s syndrome

Answer 5

Oestrogen and progesterone
Hydrocortisone
Levothyroxine
Growth hormone