Sexual health Flashcards
What are some risk factors for STIs (8)?
- < 25 years
- UPSI
- IVDU
- Immunosuppression
- Men who have sex with men (MSM)
- Lower socioeconomic status
- Multiple partners
- Sexually active
What are the important STIs to how about (9)?
- Chlamydia
- Gonorrhoea
- Trichomonas vaginalis
- HSV
- HPV
- Syphilis
- Mycoplasma genitalium
- HIV
- Chancroid
What investigations are typically done to investigate for STIs in men (3)?
- Men = first catch urine + MC&S = usually first line
- Urethral swab
- Bloods
What investigations are typically done to investigate for STIs in women (4)?
- Vulvovaginal swab (done by themselves) = usually first line
- Endocervical or high vaginal swabs
- First catch urine
- Bloods
What are the different types of swab that can be used to investigate STIs and what are they for (2)?
- Charcoal swab = MC&S
- Nucleic acid and amplification test (NAAT) swab = identification of DNA/ RNA
Who is eligible for the sexual health screening programme?
Sexually active 16-24 year olds
How frequently should 16-24 year olds be screened for STIs?
Annually or when they change partner
What is typically tested for if someone attends a GUM clinic for an STI screen (4)?
- Chlamydia
- Gonorrhoea
- Syphilis (blood)
- HIV (blood)
How far back should the contacts of those with chlamydia and gonorrhoea be traced and what should they be offered?
- Chlamydia = 6 months
- Gonorrhoea = 2 months
offer them tests
What is the most common STI in the UK?
Chlamydia
What is the full name for chlamydia?
Chlamydia trachomatis
What type of bacteria is chlamydia trachomatis?
Gram negative cocci
What are the signs/ symptoms of chlamydia (4)?
- Dysuria
- Purulent (pus) discharge
- Abnormal vaginal bleeding
- Proctitis - discomfort, discharge, bleeding (inflam in rectum)
often asymptomatic in women
How is chlamydia diagnosed?
NAAT
first catch urine or vulvovaginal swab
What are some examination finding of those with chlamydia (3)?
- Pelvic/ abdo pain
- Cervical motion tenderness
- Purulent discharge
What additional swabs should be taken considered for chlamydia in certain patient groups (2)?
- Rectal
- Pharyngeal
How should chlamydia be treated?
100mg doxycycline BD for 7 days
What are some contraindications to doxycycline (2)?
- Pregnant
- Breastfeeding
What does doxycycline do if a pregnant woman takes it?
Can cause foetal teeth discolouration
How should chlamydia be treated in pregnancy/ breastfeeding?
Azithromycin 1g stat, then 500mg OD for 2 days
What are some complications of chlamydia (7)?
- PID
- Lymphogranuloma venereum
- Infertility
- Reactive arthritis
- Neonatal infection (conjunctivitis/ pneumonia)
- Pregnancy comp (low birth weight, pre-term, ectopic, PROM)
- Fitz Hugh cutis
What is lymphogranuloma venereum?
Ulceration of genital area due to chlamydia infection
What are the signs/ symptoms of lymphogranuloma venereum (3)?
- Ulceration of genital area
- Proctitis (inflame of rectum)
- Inguinal lymphadenopathy
Where else in the body does chlamydia commonly infect?
The eye causing conjunctivitis
What is the full name for gonorrhoea?
Neiserria gonorrhoea
What type of bacteria is neiserria gonorrhoea?
Gram -ve diplococci
What are the signs/ symptoms of gonorrhoea (3)?
- Dysuria
- Odourless green discharge
- Pelvic pain
How is gonorrhoea diagnosed?
First catch urine or vulvovaginal NAAT
What is important to do before commencing antibiotics for gonorrhoea?
Charcoal swab (urethral or endocervical) for MC&S
to determine Abx resistance
How is gonorrhoea typically managed if the sensitivities are not known?
IM ceftriaxone 1g stat
What are some complications of gonorrhoea (5)?
- Septic arthritis
- Disseminated gonococcal infection
- Conjunctivitis
- Neonatal infections (ophthalmia neonatorum)
- Infection of nearby organs (proctitis, prostatitis, epididymo-orchitis)
Does chlamydia or gonorrhoea more commonly cause reactive and septic arthritis?
- Chlamydia = reactive
- Gonorrhoea = septic
What is ophthalmia neonatorum and how is it managed?
Neonatal conjunctivitis
it is a medical emergency when caused by gonorrhoea and can lead to blindness
What are the signs/ symptoms of disseminated gonococcal infection (3)?
- Polyarthralgia (migratory)
- Systemic Sx e.g. fever, fatigue
- Various non-specific skin lesions
What is the most common STI worldwide?
Trichomonas vaginalis
What sort of organism is trichomonas vaginalis?
Flagellated protazoa
What are the signs/ symptoms of trichomonas vaginalis (5)?
- Dysuria
- Yellow frothy offensive discharge
- Itching
- Strawberry cervix
- Balantitis (inflammation of penis glans)
How is trichomonas vaginalis diagnosed (2)?
- Charcoal high vagina swab + microscopy
- Men = first catch urine + microscopy
What is an additional finding in women with trichomonas vaginalis?
High vaginal pH
like in BV
How is trichomonas vaginalis managed?
Metronidazole
What else is important to do/ tell in those diagnosed with trichomonas vaginalis (2)?
- Do not drink alcohol - reacts with metronidazole and can induce hypotension
- Contact trace
What can cause ulcers in the genital region?
HSV 2
How is HSV 2 diagnosed?
PCR (swab)
How is HSV 2 treated?
Aciclovir
What causes genital warts?
HPV 6 and 11
What is the presentation of genital warts?
Painless warts on genitals
How can genital warts be prevented?
HPV vaccines
How are genital warts treated?
Podophyllotoxin cream/ imiquimod cream
What bacteria causes syphilis?
Treponema pallidum
What type of bacteria is treponema pallidum?
-ve spirochete
What are the stages of syphilis (4)?
- Primary syphilis
- Secondary syphilis
- Latent syphilis
- Tertiary syphilis
How long is syphilis incubation period?
21 days
What is the presentation of primary syphilis?
Painless ulcer at infection site (chancre)
What are the signs/ symptoms of secondary syphilis (5)?
- Maculopapular rash
- ‘Snail track’ ulcers
- Alopecia
- Low grade fever
- Lymphadenopathy
typically last 3-12 weeks
What is the presentation of tertiary syphilis?
Gummatous lesions - granulomas that can develop in multiple organs throughout the body
What is a complication of tertiary syphilis (3)?
- Neurosyphilis
- A^3 (abdominal aortic aneurysm)
- Higher risk of HIV transmission
What are the symptoms of neurosyphilis (4)?
- Headache
- Altered behaviour
- Sensory impairment
- Argyll-robertson pupil (accommodates but no light reflex)
How is syphilis diagnosed (2)?
- Serology testing
- Infection site swabs + NAAT
What serology tests are done for syphilis (2)?
- Rapid plasma reagin (RPR)
- Venereal disease research laboratory (VDRL)
How is syphilis managed?
IM Benzathine benzylpenicillin (benzathine pen g)
What is a complication of treatment for syphilis?
Jarisch-herxheimer reaction
contents of bacteria spilling in blood - a bit like tumour lysis syndrome
What STI is known for resistance to an increasing number of antibiotics?
Mycoplasma genitalium
What is the typical presentation of MG?
Urethritis
What are the signs/ symptoms of urethritis (2)?
- Dysuria
- Discharge
How is MG investigated?
- First catch/ vaginal swab NAAT
- Charcoal swab + MC&S (for macrolide resistance)
How is MG treated (2)?
- Doxycycline + azithromycin
- Moxifloxacin
What causes chancroid?
Bacteria (haemophilus ducreyi)
What are the signs/ symptoms of chancroid (3)?
- Painful genital ulceration
- Discharge
- Lymphadenopathy
How is chancroid treated?
Azithromycin
chancroid = azythromycin
What are two STI-like conditions that are not sexually transmissible?
- Bacterial vaginosis
- Thrush
What is bacterial vaginosis?
Overgrowth of bacteria, especially anaerobes, in the vagina
What is usually the cause of BV?
Loss of lactobacilli ‘the friendly bacteria’
What is the most common anaerobe causing BV?
Gardnerella vaginalis
overgrown garden??
What are some risk factors for BV (4)?
- Multiple partners
- Excessive PV cleaning
- Recent Abx
- Smoking
What reduces the risk of getting BV (2)?
- COCP
- Condom use
What is the typical presentation of BV?
Fishing smell watery grey discharge
What criteria can be used to diagnose BV?
Amstel criteria
amsterdam because they have lots of sexual partners there
What are the Amstel criteria for diagnosis of BV (4)?
- pH > 4.5
- White/ grey discharge
- Clue cells on microscopy
- +ve whiff test
3/4 for diagnosis
What are clue cells?
Epithelial cells of vagina with Gardnerella vaginalis stuck in them
How is BV managed (2)?
- Conservative advice (e.g. stop smoking, stop douching/ cleaning)
- Metronidazole
What are some complications of BV (4)?
- Increased risk of STIs
- Miscarriage/ preterm
- PROM
- Postpartum endometritis
What causes thrush?
Candida infection
What are some risk factors for thrush (4)?
- Increased oestrogen (pregnancy, fertile, COCP)
- Poorly controlled diabetes
- Immunosuppression
- Recent Abx
What are the signs/ symptoms of thrush (2)?
- Thick white ‘cottage cheese’ discharge that does not smell
- Itchy
How is thrush investigated (3)?
- Clinical diagnosis
- pH < 4.5
- Charcoal swab + microscopy (if in doubt)
How is thrush managed (2)?
- Oral fluconazole stat
or - Clotrimazole cream
What is important to inform women treated for thrush about?
Antifungal creams can damage condoms/ prevent spermicides working so alternative contraception needed for 5 days
What is pelvic inflammatory disease?
Infection and inflammation of the organs of the pelvis caused by infection ascending through the cervix
Which structures can become inflamed in PID (3)?
- Endometritis
- Salpingitis (Fallopian tubes)
- Oophoritis (ovaries)
peritonitis can occur
What causes PID most commonly (3)?
- Chlamydia = MC
- Neiserria gonorrhoea
- MG
can be caused by others such as H. influenzae, E. coli
What are the signs/ symptoms of PID (6)?
- Pelvic/ lower abdo pain
- Deep dyspareunia
- Abnormal vaginal bleeding
- Discharge
- Fever
- Dysuria
What are some risk factors for PID (5)?
- Coil
- No barrier contraception
- Multiple partners
- Younger age
- Previous PID
What are some examination finding of PID (4)?
- Abdo/ pelvic tenderness
- Cervical motion tenderness
- Discharge
- Fever
How is PID investigated (4)?
- High vaginal swabs + MC&S (often negative)
- Pregnancy test (ectopic)
- Bloods (HIV, syphilis)
- TVUSS
How is PID treated with antibiotics?
- Ceftriaxone
- Doxycycline
- Metronidazole
When should PID be referred to hospital (2)?
- Pregnant woman
- Signs of sepsis
What are some complications of PID (5)?
- Infertility
- High risk for ectopic pregnancy
- Chronic pelvic pain
- Sepsis
- Fitz-hugh-curtis syndrome
What is Fitz-hugh-curtis syndrome?
Inflammation and infection of the liver capsule
What are some causes of balanitis (3)?
- Candidia = mc
- Trichomonas vaginalis
- Lichen sclerosis
How does balanitis typically present?
White itchy lesions with thick discharge
What is a complication of balanitis?
Balanitis xerotica obliterans
long term inflammation leading to damage
What parasite can infect the pubic area?
Public lice
What is the typical presentation of pubic lice?
Severely itchy pubic area with visible movement
How are pubic lice treated?
Permethrin
What is it known as when you are not interested in sex but you want to be?
Hypoactive sexual desire disorder (HSDD)
What are 3 ways HSDD will present itself?
- Decreased sex desire
- Decreased response to partners sexual cues
- Don’t initiate sex
What are some risk factors/ causes for HSDD (3)?
- Depression/ anxiety
- DM, hypothyroid
- Meds (e.g. opioids, SSRIs)
How can HSDD be managed (4)?
- Reduce stress
- Couples therapy
- Exercise
- Flibanserin
What is failure to orgasm despite stimulation known as?
Anorgasmia
What are some risk factors/ causes of anorgasmia (6)?
- Depression/ anxiety
- Performance anxiety
- DM/ hypothyroid
- Postmenopausal
- Post hysterectomy
- Dyspareunia
How is anorgasmia managed (3)?
- Sexual education
- Clitoral vacuum (increases blood flow)
- COCP
What is involuntary contraction of the vaginal wall known as?
Vaginismus
What are some consequences of vaginismus (2)?
- No sexual penetration
- Speculum + smear impossible/ difficult
What are some risk factors/ causes of vaginismus (4)?
- Trauma
- Anxiety/ stress
- Childbirth
- FGM
How is vaginismus treated (3)?
- Sex education/ psychology
- Keigel exercises
- Vaginal dilation therapy
What is pain in vulva without an identifiable cause known as?
Vulvodynia
How is vulvodynia managed (4)?
- Reduce friction during sex (lubricants)
- Keigel
- Analgesia
- TCAs
What can be done in sex education/ psychology to improve sex (3)?
- Couples therapy
- CBT
- Different techniques e.g. clitoral stimulation/ sex toys
What is erectile dysfunction known as?
Impotence
What are some causes of impotence (7)?
- Peripheral vascular disease/ atherosclerosis
- DM
- Spinal cord damage
- High prolactin
- Stress/ performance anxiety
- MS
- Meds e.g. SSRIs
How is erectile dysfunction managed (2)?
- Keigel exercises
- Sildenafil
What is important to assess in men with erectile dysfunction?
QRISK score + do bloods
at risk of PVD + CHD
What is premature ejaculation?
Ejaculation within 1 minute of sex
What are some causes of premature ejaculation (4)?
- Performance anxiety
- Watching pornography
- Hyperthyroid
- Sex abuse
How is premature ejaculation managed (5)?
- Sex therapy
- Stop, start, squeeze
- Lidocaine cream
- Keigel exercises
- Dapoxetine
What is retrograde ejaculation?
When the sperm is ejaculated into the bladder due to the urethral sphincter not contracting
What are some causes of retrograde ejaculation (2)?
- Transurethral resection of the prostate (TURP)
- ACE-i
How is retrograde ejaculation diagnosed?
Post ejaculatory void = lots of sperm
How is retrograde ejaculation treated (2)?
- Medications (tighten neck of bladder) e.g. TCAs
- Surgery
What can cause a wonky erection?
T3 collagen deposits in tunica albuginae
What is it known as when you have a wonky erection due to collagen deposits?
Peyronie
What condition is peyronie associated with?
Dupuytrens contractures
How is peyronie diagnosed?
Penile USS
How is peyronies managed (2)?
- Surgical straitening
- Injection of collagenase