Sex hormones Flashcards
1
Q
What is the rate limiting step/enzyme in steroid hormone synthesis?#
A
Cholesterol–> pregnenolone by desmolase (CYP11A1)
2
Q
What stimulates the initial step of steroid hormone synthesis?#
A
ACTH and Ang II
3
Q
After the initial rate limiting step, what 2 enzymes are required for synthesis of both aldosterone and cortisol?#
A
3B Hydroxysteroid dehydrogenase and 21 hydroxylase
4
Q
11 B hydroxylase is requried for synethsis of _____.#
A
Cortisol
5
Q
______ is required to convert pregnenolone and progesterone and DHEA, both precursors of adrenal androgens.#
A
17a hydroxylase
6
Q
What is the optimal temperature for spermatogenesis and how is it reached?
A
less than 37. Blood supply with pampinor
