Session 3 Flashcards
The mid gut is connected to the yolk sac at its
Midpoint
What happens to the midgut in week 6
Grows faster than abdominal cavity
Protrudes through abdominal wall and tiny umbilical cord (physical herniation)
The herniated midgut forms a
Loop with the superior mesenteric artery within the umbilical cord
What do distal and proximal parts of herniated midgut loop form
Distal- caecal bulge
proximal- convoluted
Explain mid gut loops rotation
Rotates whilst in umbilical cord- returns to abdomen around week 10
3 x 90 degree rotations
Abnormal rotations are fairly common
What may happen if an abnormally large opening between the abdominal cavity and the umbilical cord persists
An umbilical hernia may be present
What is Meckel’s diverticulum
Persistent yolk sac remnant in the midgut
The hindgut forms what
Distal part of transverse colon through to superior portion of anal canal
Where does the hindgut end at first
Cloacal membrane- separates it from proctodaeum
What happens when the cloacal membrane ruptures
The hindgut is connected to the exterior, the anal canal therefore has dual origin
Initially the developing intestines have
No lumen- canalisation occurs in weeks 6-8
What happens if canalisation fails
Partial or full obstruction. Recanalisation occurs in oesophagus, bile duct and SI
What is pyloric stenosis
Hypertrophy of pyloric sphincter
Not recanalisation failure
Causes projectile vomiting in infants
What is Gastroschisis
Failure of closure of the abdominal wall following folding of embryo- gut tube and derivatives outside body cavity
What is Omphalocoele
Persistence of the physiological herniation of midgut
Anal canal is divided into
Superior and inferior parts by the pectinate line
Differ with regards to vasculature, nerve supply, lymphatic drainage and histological features
What is the cloaca
Region at end of hindgut
Divides into anterior urogenital sinus and posterior anorectal canal
What makes up saliva
Primarily water
Oral hygiene- IgA, lysozymes and lactoferrin
Digestion- amylase and lingual lipase
What is the word for reduced flow of saliva in oral cavity
Xerostomia
What are the 3 paired salivary glands
Parotid, submandibular, sublingual
Primary regulator of saliva production
Autonomic system- particularly parasympathetic
What results in dry mouth
Anything that reduces parasympathetic innervation