Large Intestine Basics Flashcards

1
Q

Large intestine location

A

Caecum to anal canal

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2
Q

Cell type in large intestine

A

Columnar epithelium

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3
Q

Role of LI

A

Removes water from indigestible gut contents, turns chyme into semi solid

Production of vitamins

Temporary storage until defacation

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4
Q

environment of LI

A

Micro biome- contains lots of commensal bacteria

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5
Q

Colonic mucosa gets majority of nutrients from where

A

Not from blood
Short chain fatty acids derived from the fermentation of dietary fibre
By-products include CO2, Methane and H+ gas

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6
Q

Ascending and descending colon position

A

Retroperitoneal

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7
Q

Transverse colon has its own

A

Mesentary (transverse mesocolon)

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8
Q

Sigmoid colon has its own

A

Mesentary

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9
Q

Positioning of rectum

A

Upper 1/3 intra-peritoneal
Middle 1/3 retroperitoneal
Lower 1/3 no peritoneum

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10
Q

Arterial supply to LI midgut component

A

Midgut component- superior mesenteric artery

Ilio-colic = caecum
Right colic = ascending colon
Middle colic = transverse colon

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11
Q

Arterial supply to LI hindgut component

A

inferior mesenteric artery

left colic - descending colon
Sigmoid- descending colon

Superior rectal artery- upper 1/3 rectum

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12
Q

venous drainage of LI (midgut and hindgut)

A

Midgut drains into superior mesenteric vein

Hindgut drains into inferior mesenteric vein

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13
Q

venous drainage of LI rectum

A

Upper 1/3 drains into superior rectal vein

Middle and lower 1/3ds drain into systemic venous system- site of Portosystemic anastomoses

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14
Q

Large intestine and small intestine anatomical differences

A

LI shorter and wider
LI has crypts not villi

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15
Q

Anatomy of bands of large intestine

A

External longitudinal muscle is incomplete
3 distinct bands (teniae coli)
Haustra are sacculations caused by contraction of teniae coli

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16
Q

Explain water absorption in the colon

A

Facilitated by ENaC

Approx 1500 mls of water enter colon/day, <100 mls excretedin faeces

Most absorption in proximal colon

Induced by aldosterone

Much tighter tight junctions - allows bigger gradient to form, less back diffusion of ions