Sesh 1: Intro And Investigative Techniques Flashcards

1
Q

What % of body mass is water?

A

60%

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2
Q

What is gout, and what joint does it most commonly affect?

A

Defective metabolism of uric acid causing crystals to form in joints.
Mainly affects the toe joint.

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3
Q

What is pseudogout and what joint does it most commonly affect?

A

A form of arthritis caused by formation of a different type of crystals in joints, mainly affecting the knee.

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4
Q

Name a way of distinguishing between gout and pseudogout.

A

Via polarised light microscopy:

  • gout- yellow, needle-shaped crystals
  • pseudogout- blue, rod-shaped crystals
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5
Q

What imaging process does confocal microscopy resemble?

A

CAT scans

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6
Q

High frequency ultrasound waves travel _______ and contain ____ energy than low frequency.

A
  1. Further

2. Less

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7
Q

Can TEM visualise living tissue?

A

No, as uses electron beam generated in a vaccum.

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8
Q

Name the 3 types of cell in the body that exist as single cells.

A
  1. Spermatazoa
  2. Ova
  3. Red blood cells
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9
Q

Females’ haematocrit is usually ________ than males’.

A

Lower- around 37-47% versus 40-54%.

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10
Q

Above what temperature is considered hyperthermia?

A

37.8 C

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11
Q

Below what temperature is considered hypothermia?

A

36 C

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12
Q

Name a therapeutic use of hyperthermia.

A

Makes cancer cells more sensitive to radiation in radiotherapy.

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13
Q

How can infection cause pyrexia?

A

Macrophages that fight the infection produce circulating pyrogens that bind to R’s in the hypothalamus, and raise the body temp set point.

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14
Q

What is a rigor?

A

A chill with shivering at fever onset. It’s an extreme reflex response which indicates serious infection.

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15
Q

What is a goitre?

A

Swelling of the neck/ thyroid gland due to over/underactive thyroid.

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16
Q

Define prevalence.

A

The number of alive patients with the disease either over a certain time (period) or at a specific time (point). Indicates how widespread a disease is.

17
Q

Define incidence.

A

The rate of new cases of a disease. Indicates risk of disease

18
Q

What steps do you need to take to image tissues via light microscopy?

A
  1. Preserve- formalin
  2. Embed- paraffin
  3. Stain- e.g. H&E