Serotonin and Dopamine Flashcards by Ryan Hutten | Brainscape

Q

5-HTP mechanism of action

A

precursor for serotonin (5HT)

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Q

5-HTP indication

A

depression

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Q

Buspirone mechanism of action

A

5-HT1A partial agonist

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Q

Buspirone indication

A

Anxiety/depression

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Q

Buspirone side effects

A

Early increase in anxiety

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Q

Sumatriptan mechanism of action

A

5-HT1D agonist

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Q

Sumatriptan indication

A

Migraines

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Q

Sumatriptan side effects

A

Coronary vasoconstriction

Contraindication: pts with coronary artery disease

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Q

Risperidone mechanism of action

A

5HT2A/2C antagonist

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Q

Risperidone indication

A

depression, schizophrenia with psychosis

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Q

Risperidone side effects

A

weight gain

akathisia

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Q

Odansetron mechanism of action

A

5-HT3 antagonist

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Q

Odansetron indication

A

Chemotherapy induced emesis

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Q

Fluoxetine mechanism of action

A

SSRI

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Q

Fluoxetine indication

A

Depression, OCD, anxiety, panic disorder, PTSD, social phobia

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Q

Fluoxetine side effects

A

Sexual dysfunction

Insomnia

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Q

Sertraline mechanism of action

A

SSRI

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Q

Sertraline indication

A

Depression, OCD, anxiety, panic disorder, PTSD, social phobia

Q

Sertraline side effects

A

Sexual dysfunction

Insomnia

Q

L-DOPA mechanism of action

A

Dopamine precursor

Q

L-DOPA indication

A

Parkinson’s disease

Q

L-DOPA side effects

A

Arrhythmia/Dyskinesia

Q

Bromocriptine mechanism of action

A

D2 agonist

Q

Bromocriptine indication

A

Parkinson’s disease

Q

Carbidopa mechanism of action

A

Aromatic acid decarboxylase inhibitor

Q

Carbidopa indication

A

Parkinson’s disease

Q

Carbidopa side effects

A

Same as L-DOPA

Arrhythmia/Dyskinesia

Q

Selegiline mechanism of action

A

MAO-B inhibitor

Q

Selegiline indication

A

Parkinson’s disease

Q

Tolcapone mechanism of action

A

COMT inhibitor

Q

Tolcapone indication

A

Parkinson’s disease

Q

Methylphenidate mechanism of action

A

Dopamine reuptake inhibitor

Q

Methylphenidate indication

A

ADHD

Q

Methylphenidate side effect

A

Tachycardia (amphetamine)

Q

Metaclopramide mechanism of action

A

D2 antagonist

Q

Metaclopramide indication

A

Nausea

Q

Metaclopramide side effect

A

Akathisia

Q

Haloperidol mechanism of action

A

D2 antagonist

Q

Haloperidol indication

A

Psychosis

Q

Haloperidol side effects

A

Extra-pyramidal motor disturbances

Q

Trazadone mechanism of action

A

5HT2A/2C antagonist and SSRI

Q

Trazadone indication

A

Anxiety and depression

Q

Trazadone side effects

A

Suicidality early after initiation

“I’m (traza)done with this shit”