Serotonin and Dopamine Flashcards by Ryan Hutten

Q

5-HTP mechanism of action

A

precursor for serotonin (5HT)

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Q

5-HTP indication

A

depression

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Q

Buspirone mechanism of action

A

5-HT1A partial agonist

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Q

Buspirone indication

A

Anxiety/depression

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Q

Buspirone side effects

A

Early increase in anxiety

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Q

Sumatriptan mechanism of action

A

5-HT1D agonist

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Q

Sumatriptan indication

A

Migraines

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Q

Sumatriptan side effects

A

Coronary vasoconstriction

Contraindication: pts with coronary artery disease

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Q

Risperidone mechanism of action

A

5HT2A/2C antagonist

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Q

Risperidone indication

A

depression, schizophrenia with psychosis

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Q

Risperidone side effects

A

weight gain

akathisia

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Q

Odansetron mechanism of action

A

5-HT3 antagonist

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Q

Odansetron indication

A

Chemotherapy induced emesis

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Q

Fluoxetine mechanism of action

A

SSRI

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Q

Fluoxetine indication

A

Depression, OCD, anxiety, panic disorder, PTSD, social phobia

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Q

Fluoxetine side effects

A

Sexual dysfunction

Insomnia

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Q

Sertraline mechanism of action

A

SSRI

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Q

Sertraline indication

A

Depression, OCD, anxiety, panic disorder, PTSD, social phobia

Q

Sertraline side effects

A

Sexual dysfunction

Insomnia

Q

L-DOPA mechanism of action

A

Dopamine precursor

Q

L-DOPA indication

A

Parkinson’s disease

Q

L-DOPA side effects

A

Arrhythmia/Dyskinesia

Q

Bromocriptine mechanism of action

A

D2 agonist

Q

Bromocriptine indication

A

Parkinson’s disease

Carbidopa mechanism of action

Aromatic acid decarboxylase inhibitor

Carbidopa indication

Parkinson's disease

Carbidopa side effects

Same as L-DOPA | Arrhythmia/Dyskinesia

Selegiline mechanism of action

MAO-B inhibitor

Selegiline indication

Parkinson's disease

Tolcapone mechanism of action

COMT inhibitor

Tolcapone indication

Parkinson's disease

Methylphenidate mechanism of action

Dopamine reuptake inhibitor

Methylphenidate indication

ADHD

Methylphenidate side effect

Tachycardia (amphetamine)

Metaclopramide mechanism of action

D2 antagonist

Metaclopramide indication

Nausea

Metaclopramide side effect

Akathisia

Haloperidol mechanism of action

D2 antagonist

Haloperidol indication

Psychosis

Haloperidol side effects

Extra-pyramidal motor disturbances

Trazadone mechanism of action

5HT2A/2C antagonist and SSRI

Trazadone indication

Anxiety and depression

Trazadone side effects

Suicidality early after initiation | "I'm (traza)done with this shit"