Seronegative Inflammatory Arthritis Flashcards
rheumatoid arthritis is 70%-80% seropositive for what
rheumatoid factor and
anti-CCP antibodies
what is spondyloarthritis
it is an umbrella term for inflammatory diseases that affect entheses and joints,
Involvement of the sacroiliac joints and spine
– Sometimes with an oligoarticular peripheral arthritis
give two examples of acial SpA
Ankylosing spondylitis
– Non radiographic axial SpA
give four examples of periphial SpA
Psoriatic Arthritis
– Enteropathic Arthritis
– Reactive Arthritis
– Juvenile onset SpA
an individual has morning stiffness for longer than 30 mins, peripheral arthritis, enthesitis, dactylitis, night pain, buttock hip neck pain and chronic low back pain, improves with excercise, what is this likely to be
Axial Spondyloarthritis (AxSpA)
what are the symptoms of AxSpA
Symptoms – Chronic low back pain – Buttock/hip/ neck pain – Improves with exercise – Night pain – Morning stiffness >30 mins – Peripheral arthritis – Enthesitis – Dactylitis
what age of does AxSpa tend to affect and gender
age 20-40 affects men more than women
how do you manage someone with axial SpA
Nsaids, excercise and BASDAI on two occasions 12 weeks apart
what does BASDAI stand for
Bath Ankylosing Spondylitis Disease Activity Index is a validated diagnostic test which allows a physician, usually a rheumatologist, to determine the effectiveness of a current drug therapy, or the need to institute a new drug therapy for the treatment of Ankylosing spondylitis (AS).
what are the Clinical Features of PsA
Peripheral arthritis • Axial disease • Enthesitis • Dactylitis • Skin and nail disease!!
if PsA is polyarticular describe what areas are involved
Involvement of many small joints usually in hands and feet
– Most common type >50%
– Rarely get rapid joint damage (Arthritis mutilans)
if PsA is oligoarticular describe what areas are involved
– Affects a few large joints
– Eg knee, ankle, elbow
appreciate Psoriatic Arthritis: Nail Changes which are..
yellowing, pitting etc
what is Asymmetric oligoarthritis
his type of psoriatic arthritis affects fewer than five small or large joints in the body but does not necessarily occur on both sides of the body. (For example, a person might experience joint pain in one elbow but not the other.
what is arthritis mutilans
Arthritis mutilans is a rare medical condition involving severe inflammation damaging the joints of the hands and feet, and resulting in deformation and problems with moving the affected areas; it can also affect the spine.
