serological diagnosis of disease

Question 1

serology is commonly used to diagnose _____

Answer 1

viruses

Question 2

primary immune response

Answer 2

response the first time the virus/antigen is encountered

Question 3

secondary immune response

Answer 3

response the body has to a virus/antigen that it has encountered before

Question 4

IgM antibody titer to a particular antigen in the acute phase sample infers either:

Answer 4

• a recent initial vx for that disease (check vx hx)
• a current disease stat

Question 5

IgG antibody titer for a particular antigen in the acute phase sample infers either:

Answer 5

• a recent booster vx (check vx hx)
• the animal has recovered from this disease in the past (check hx if possible)
• a current disease state

Question 6

convalescent stage

Answer 6

• stage after having the disease
• IgG antibodies are present but remain stable

Question 7

actively infected state

Answer 7

• the animal is currently ill
  IgG antibody titer is rising

Question 8

second blood sample sent to the lab

Answer 8

convalescent phase sample

Question 9

acute period of disease

Answer 9

• period of disease incubation
• before clinical signs
• host is febrile
• the greatest number of microorganisms present
• few antibodies because the host has not had enough time to make them
• greatest potential of transmission to other animals in the herd

Question 10

covalence period

Answer 10

• about 5-10 days the animal starts to produce antibodies
• antibody production lasts about one month after clinical signs
• this is when the convalescent serum is taken