EXAM 12: Immune reactions of blood

Question 1

what happens (broadly) if the wrong blood is transfused

Answer 1

• severe reactions
• often death

Question 2

Isoantibodies

Answer 2

• antibodies in the serum of one individual, directed against the antigens of RBCs of other individuals of the same species
• are naturally occurring
• level will increase if the individual has been transfused with a foreign blood type in the past
• if 2 different blood types are used clumping and occasionally cell rupture will occur
• we use humans as our example sp

Question 3

hemagglutination

Answer 3

clumping, and sometimes cell rupture

Question 4

what are the two important isoantibodies

Answer 4

A and B
(O is not an antigen, it’s the lack of one)

Question 5

cross-matching

Answer 5

• simple test used to determine if two blood types are compatible without specifically identifying antigens involved
• involves testing the blood of the donor against the serum of the recipient, if isoantibodies are present, hemagglutination will occur