Sepsis

Question 1

what is the definition of sepsis

Answer 1

systemic illness caused by microbial invasion of normally sterile parts of the body
unbalanced of anti- inflammatory and inflammatory mediators leading to organ failure

Question 2

what does qSOFA mean

Answer 2

quick systemic organ failure assessment

Question 3

what does it assess

Answer 3

1 for low blood pressure systolic <100
1 for high res rate >22
1 for altered mental state <15 GCS

Question 4

name physical barriers to sepsis

Answer 4

musical barrier
skin
epithelial lining

Question 5

describe the pathophysiology of sepsis

Answer 5

uncontrolled inflammatory response

inability to clear infection

Question 6

name the first phase in pathogenesis of sepsis

Answer 6

release of bacterial toxins, bacterial invasion into the body tissues

Question 7

name the second phase

Answer 7

release of mediators in response to infection

Question 8

name the 2 types of mediators

Answer 8

pro inflammatory mediators

compensatory anti-inflammatory mediators

Question 9

name stage 3

Answer 9

effects of specific excessive mediators

Question 10

describe general clinical features of sepsis

Answer 10

fever>38
chills, sweats
tachycardia>90
tachyopnea>20
altered mental status

Question 11

what is sepsis 6

Answer 11

give 3:oxygen, IV fluids, IV antibiotics

take 3: blood cultures, blood lactate, urine output