Sepsis

Question 1

A life-threatening condition that arises when the body’s response to an infection injures its own host

Answer 1

Sepsis

Question 2

It is characterised by a life-threatening organ dysfunction due to a dysregulated host response

Answer 2

Sepsis

Question 3

A subset of sepsis where profound circulatory, cellular, and metabolic abnormalities substantially increase mortality

Answer 3

Septic shock

Question 4

Bacteria in the blood

Answer 4

Bacteraemia

Question 5

Pathophysiology of sepsis

Answer 5

immune system, inflammation, activation of coagulation

Question 6

A protective response to eliminate the cause of injury and any necrotic tissue present as a result of injury

Answer 6

inflammation

Question 7

3 stages of inflammation

Answer 7

vasodilation, increased vascular permeability, increased O2 demand

Question 8

redness

Answer 8

rubor

Question 9

swelling

Answer 9

tumor

Question 10

heat

Answer 10

calor

Question 11

pain

Answer 11

dolar

Question 12

It causes and maintains vasodilation which helps to make capillaries to be more permeable

Answer 12

nitric oxide

Question 13

responsible for the pain at the site of inflammation

Answer 13

bradykinin

Question 14

they act directly to neutralise pathogens, mobilise WBC and amplify the immune response

Answer 14

complement proteins

Question 15

helps clot formation by turning fibrinogen into fibrin

Answer 15

thrombin

Question 16

complex group of proteins which help WBC to function, attract them to the area, and modulate inflammation

Answer 16

interleukins

Question 17

a pro-inflammatory cytokine

Answer 17

tumour necrosis factor (TNF)