sensory transduction Flashcards

1
Q

what is a graded potential

A

Get cell to threshold so it can fire action potentials

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

a beta fibres

A

large myelinated- touch, pressure, vibration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

a delta fibres

A

small myelinated- cold, fast pain and pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

c fibres

A

unmyelinated- slow pain and warmth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what fibres is propioception stimulated by

A

A alpha and A beta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

mechanoreceptors

A

project up through ipsilateral dorsal columns
synapse in cuneate and gracile nuclei
2nd order fibres corss over midline in brainstem and project to reticular formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

where do thermorecceptors and nociceptors synapse

A

dorsal horn
2nd order fibres cross over at midline
project up through lateral spinothalamic tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

how do NSAIDS work

A

prostaglandin sensitise nociceptors to bradykinin
inhibit cyclo-oxygenase which converts arachidonic acid to postaglandins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

how do local anesthetics work

A

block sodium action potential and therefrom all axonal transmission

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

how do opiates work

A

reduces sensitivity to nociceptors and block transmitter release in the dorsal horn
activate descending inhibitory pathways

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

gate control theory

A

nociceptor fibres come into the dorsal horn and immediately synapse onto 2nd order neurons. decussate and project up thalamus in the lateral spinothalamic tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly