Sensory Systems (Incl. Physiology of Pain) Flashcards

1
Q

What structure does a light touch receptor have?

A

Tactile (Meissner’s) corpuscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What structure does a touch receptor have?

A

Tactile (Merkle’s) corpuscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What structure does a pain receptor have?

A

Free nerve ending

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What structure does a deep pressure receptor have?

A

Lamellated (Pacinian) corpuscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What structure does a warmth receptor have?

A

Ruffini corpuscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What factors determine acuity?

A

Density of innervation and size of receptive fields

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which types of sensation are carried in AB (large myelinated)fibres?

A

Touch, pressure and vibration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which types of sensation are carried in A delta (small myelinated) fibres?

A

Cold, ‘fast’ pain and pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which types of sensation are carried in C (unmyelinted) fibres

A

Warmth and ‘slow’ pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which fibres carry proprioception?

A

Aa and AB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Where do primary afferent fibres enter the CNS?

A

Dorsal root ganglia and cranial nerve ganglia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What path do mechanoreceptive fibres (Aa and AB) take?

A

They project straight up the ipsilateral dorsal columns, synapse in the cuneate and gracile nuclei, decussate in the brain stem and project to the reticular formation, thalamus and cortex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What path do thermoreceptive and nociceptive fibres (A delta and C) take?

A

They synapse in the dorsal horn, cross over the midline in the spinal cord and project up the contralateral spinothalamic tract to the reticular foramen, thalamus and cortex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What effect does damage to the dorsal columns have on the transmission of sensory information?

A

Loss of touch, vibration and proprioception below the lesion on the ipsilateral side

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What effect does damage to the anterolateral quadrant have on the transmission of sensory information?

A

Loss of nociceptive and temperature sensation below the lesion on the contralateral side

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What activates nociceptors?

A

Low pH, heat and local chemical mediators (bradykinin, histamine, prostaglandins etc.

17
Q

How do NSAIDs work?

A

They inhibit cyclo-oxygenase which converts arachidonic acid to prostaglandins

18
Q

How do local anaesthetics work?

A

They block the sodium AP and therefore all axonal transmission

19
Q

How do opiates work?

A

They:

  • reduce sensitivity of nociceptors
  • block transmitter release in the dorsal horn
  • activate descending inhibitory pathways