Pathology of Head Injury Flashcards

1
Q

What is the primary insult of head injury?

A

Focal/diffuse brain trauma

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2
Q

What are the secondary insults of brain injury?

A

Hypotension, hypoxia, infection and haematoma

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3
Q

What is used to initially assess the severity of the head injury?

A

Glasgow coma scale:
Mild: 13-15
Moderate: 9-12
Severe: 3-8

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4
Q

What are the significant consequences of head injuries?

A

Permanent physical disability, post traumatic epilepsy, intracranial infection, psychiatric illness, chronic subdural haemorrhage, ‘punch-drunk’ dementia and fatality (uncommon)

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5
Q

What are the three most common causes of injury?

A

Accidental, homicidal and natural disease

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6
Q

What is the cause of a linear skull fracture?

A

Blow or fall onto the top or side of the head

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7
Q

What is a depressed skull fracture?

A

When skull fragments are pushed inwards damaging the structures underneath

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8
Q

What is a comminuted skull fracture?

A

A fragmented skull with a mosaic pattern

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9
Q

What is a ring fracture?

A

Fracture line encircling the foramen magnum caused by a fall from a height, usually landing on the feet and causing the skull base and cervical spine to be forced together

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10
Q

What is a contre-coup fracture?

A

Fracturing of the orbital plates (anterior fossa) due to a fall onto the back of the head

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11
Q

What happens if an increase in intracranial pressure is left untreated?

A

It will ultimately cause death due to compression of the brainstem caused by herniation of the cerebellar tonsils into foramen magnum

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12
Q

Which artery is the most common cause of an extradural haemorrhage?

A

Middle meningeal artery

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13
Q

Which vessels commonly cause a subdural haemorrhage?

A

Bridging veins

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14
Q

What is the cause of a Traumatic basal SAH?

A

Forceful impact to the upper part of the side of the neck causing an abrupt rotational movement of the head leading to rupture of the vertebra-basilar circulation

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15
Q

How is traumatic diffuse axonal injury confirmed?

A

Microscopy of the brain tissue

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16
Q

Which parts of the brain are particularly susceptible to developing tDAI?

A

Corpus callosum, para-sagittal white matter, posterior internal capsule, dorsolateral aspects of the rostral brainstem and the cerebellar peduncles

17
Q

What are the main causes of tDAI?

A

Vehicular collisions or falls from height causing shearing of the axons