sensory and motor neuroscience (intro to motor control) Flashcards
explain the definition of functional segregation
the motor system is divided into a number of different areas that control different aspects of movement
explain the definition of hierarchical organisation
the motor system is organised in a hierarchical fashion
sensory ___ enter the spinal cord via the dorsal root
sensory afferents enter the spinal cord via the dorsal root
sensory afferents enter the spinal cord via what
the dorsal root
sensory afferents enter _____ via the dorsal root
spinal cord
motor neurons leave the spinal cord via what
ventral root
what neurons leave the spinal cord via the ventral root
motor neurons
alpha motor neurons (or lower motor neurons) innervate what
skeletal muscles
what neurotransmitter do alpha motor neurons release
acetylcholine
at what synapse do alpha motor neurons release acetylcholine
neuromuscular junction
what neurons innervate skeletal muscle
alpha motor neurons
what neurons are clustered into spinal motor nuclei
alpha motor neurons
alpha motor neurons are clustered into what
spinal cord nuceli
all of the motor neurons in a nucleus innervate what
a single muscle
_____ in a nucleus innervate a single muscle
all of the motor neurons in a nucleus
each individual muscle fibre is innervated by how many motor neurons
each individual muscle fibre is innervated by only one motor neuron
each motor neuron can innervate how many fibres
many
a motor neuron and all of the fibres it innervates is known as what
a motor unit
define a muscle twitch
when a motor neuron fires an action potential, the muscle fibres of the motor unit contract, then relax
what does this statement explain
when a motor neuron fires an action potential, the muscle fibres of the motor unit contract, then relax
a muscle twitch
what is a tetanus
if the firing rate is high enough, an individual muscle twitches fuse together forming a tetanus
a continuous contraction
the higher the firing rate of a tetanus the
(finish the sentence)
the higher the force of contraction
one way of increase the force of contraction is increasing the firing rate, what is another way
recruiting more motor units
in what order are motor neurons recruited
small fine units - requires activation of S units
as more force is required, increasing number of F units
what is the difference between S and F units
F units contain larger numbers of muscle fibres
what kind of athlete would require larger number of S units
marathon runner
why would a marathon runner require more S units
(S)low contraction speed, highly fatigue resistant
contains I slow-twitch muscle fibres
motor neurons have small cell bodies and dendritic trees
what does a motor neuron look like
small cell bodies and dendritic trees
how is FR known as
fast fatigue resistant
what kind of athletes would need FR
800/1500 metre runners
why would a 800/1500m runner need FR
fast contraction speed
intermediate force
fatigue resistant
contains type IIa (fast twitch, high fatigue resistant
motor neurons have larger cell bodies
what is FF motor unit
Fast fatiguable
what athletes would require FF motor units
60/100m runners
why would 60/100m athletes require FF motor units
fast contraction speed, low fatigue resistant
contain type IIb/x
fast twitch low fatigue resistant
muscle fibres have large cell bodies
list the types of motor units and arrange them regarding the size of their cell bodies (smallest to largest)
S - small cell body and dendritic trees
FR - larger cell bodies
FF - large cell bodies
explain the size principle
orderly activation of motor units according to their size of cell bodies of their alpha motor units
-> smaller motor neurons are activated first
in the size principle, why are smaller motor neurons activated first
small surface area
-> increased membrane resistance which means more rapid depolarisation due to
V=IR
what is the speed of reflexes
rapid -> automatic
how are reflexes generated
by the circuitry of the spinal cord
what do reflexes provide
feedback adjustments to environmental perturbations
-> increase in muscle length with a reflex contraction
as well as reflexes controlling automatic behaviour, the same circuitry that mediates reflexes can also play an important role in what
voluntary movement
how can the circuitry that mediates reflexes can also play a role in voluntary movement ?
the same interneurons that coordinate excitation of extensor and inhibition of flexor muscles during the stretch reflex also coordinate contraction during voluntary movement
muscle spindles contain specialised what
muscle fibres
what are the principle receptors mediating proprioception
muscle spindles
muscle spindles contain specialised muscle fibres, and are the principle receptors mediating what
proprioception
what is proprioception
perception or awareness of the position and movement of the body
muscle stretching (increasing length) causes stretch sensitive _____ channel to open and depolarise sensory fibres
cation (Na+)
muscle stretching (increasing length) causes cation channels to open and do what
depolarise sensory fibres
muscle stretch causes the activation of what
Ia spindle afferents
Ia spindle afferents make _____ connections with alpha motor neurons
monosynaptic
Ia spindle afferents make monosynaptic connections with what
alpha motor neurons
Ia spindle afferents make monosynaptic connections with aloha motor neurons innervating the same muscle causing ________
contraction
in the stretch reflex, at the same time of Ia afferent fibres causing contraction, inhibitory neurons inhibit the activation of what
antagonist muscles
in the muscle spindle
what do gamma motor neurons cause the intrafusal fibres to do
contract - thus control sensitivity of the muscle spindle
gamma motor neurons maintain muscle spindle sensitivity during
muscle contraction
gamma motor neurons modulate the gain of
the stretch reflex
when do gamma motor neurons exhibit their highest activity
dynamic movements
falling
where is the golgi tendon
located at the transition between muscle and tendon
what does the golgi tendon organ signal the force of
muscle contraction (responds linearly on a graph)
golgi tendon organs send __ afferents that contract Ib inhibitory neurons
Ib
golgi tendon sends Ib afferents that contract what
Ib inhibitory interneurons
Golgi tendon
an increase in muscle force thus causes a reflex ______ of the same muscle
inhibition
as the golgi tendon organs send Ib afferents that contract Ib inhibitory interneurons
Ib interneurons receive input from where (2)
cutaneous and joint receptors
what do cutaneous afferents trigger
a reduction in muscle contraction when a limb contacts an object in the course of movement
the fact that when golgi tendon organs send Ib afferents that contract Ib inhibitory interneurons, what does this allow
may protect the muscle from excessive contraction - also serves to keep muscle tension within optimal range
the fact that when golgi tendon organs send Ib afferents that contract Ib inhibitory interneurons, what does this allow
may protect the muscle from excessive contraction - also serves to keep muscle tension within optimal range
where are cutaneous nociceptors located
skin
what do the sensory terminals of cutaneous nociceptors respond to
damaging stimuli
how do the terminals of cutaneous nerve endings differ
the free nerve endings are without a specialised sensory structure
A delta fibres respond to what
extremes of temperature or strong mechanical forces
Unmyelinated C fibres respond to what
types of noxious stimulation
nociceptor afferents can trigger what in response to a painful cutaneous stimuli
a withdrawal reflex
flexion withdrawal occurs after what
a painful stimulus
nociceptors afferents make what connections with motor neurons innervating a flexor muscle
nociceptors afferents make polysynaptic excitatory connections with motor neurons innervating a flexor muscle
nociceptor afferents make poly synaptic connections with what motor neurons innervating a flexor muscle
nociceptor afferents make polysynaptic excitatory connections with motor neurons innervating a flexor muscle
nociceptor afferents make polysynaptic excitatory connections with motor neurons innervating what
flexor muscle
flexor and crossed extensor reflexes
connections with inhibitory interneurons cause inhibition of what
antagonist extensor muscle
flexor and crossed extensor reflexes
connections with what cause inhibition of the antagonist extensor muscle
connections with inhibitory neurons cause inhibition of the antagonist extensor muscle
flexor and crossed extensor reflexes
what pathway causes an opposite pattern of extensor activation and flexor inhibition that provides postural support
contralateral pathway
what does the contralateral pathway cause
an opposite pattern of extensor activation and flexor inhibition that provides postural support
what do cutaneous mechanoreceptors provide
sensory feedback from the skin
cutaneous mechanoreceptors forces ion channel open that
depolarise the receptor neuron
meissner’s corpuscles exhibit what fibres
RA1 fibres
Pacinian corpuscles exhibit what fibres
RA2 fibres
Merkel disk receptors exhibit what fibres
SA1
Ruffini endings exhibit what fibres
SA2
where are meissner’s corpuscles located
what do they respond to
- superficially
- respond to stroking, flutter
Pacinian corpuscles are located where
and what do they respond to
- deeper tissues
- respond to vibration
where are Merkel disk receptors located and what do they respond to
- superficially
- pressure and texture
what do Ruffini endings respond to
skin stretch
cutaneous feedback and precision grip
meissner’s corpuscles detect what during precision lifting
microslips
cutaneous feedback and precision grip
meissner’s corpuscles detect microslips during what
precsion lifting
what corpuscles detect microslipds during precision lifting
meissner’s corpuscles
when meissner’s corpuscles detect a microslip during precision lifting what does this cause
a reflex increase in grip ensuring the object does not fall
investigating the deep tendon reflex in the wrist (supination) can be used to assess the functional integrity of what spinal cord level
C5-C6
investigating the deep tendon reflex in the biceps (elbow) can be used to assess the functional integrity of what spinal cord level
C5-C6
investigating the deep tendon reflex in the triceps (elbow) can be used to assess the functional integrity of what spinal cord level
C7
investigating the deep tendon reflex in the quadriceps (knee) can be used to assess the functional integrity of what spinal cord level
L3-L4
investigating the deep tendon reflex in the ankle (gastrocnemius) can be used to assess the functional integrity of what spinal cord level
S1