Senses Flashcards
How is the eye able to move?
It contains extraocular muscles
How does light energy pass to the optic nerve?
Via the cornea, past the lens and toward the fovea
What is the job of photoreceptors?
Converge light energy and neural activity
What types of photoreceptors are there?
Rod and cone cells
What do rod cells detect?
They are achromatic, so detect changes to light intensity
What do cones cells detect?
The are trichromatic, so allow colour vision
What function do bipolar cells have?
They create a direct pathways from photoreceptors to ganglion cells
What do retinal ganglion cells do?
They leave the eye and form the optic nerve
How is retinal change caused by rhodopsin or iodopsin?
They absorb the photon in the disc membrane, changing the retinal schiff base cofactor, leading to retinal change
What does retinal change cause?
A series of intermediates leading to a G protein activating transducin
What effect does transducin have in the eye?
Activates cGMP phosphodiesterase, converting cGMP to 5’cGMP
Photoreceptor Na+ channels close due to what change?
A net decrease in cGMP concentration
Outer segments of the photoreceptors become hyper polarised due to what change?
The decreased Na+ inside the cell
Outer photoreceptors hyper polarisation causes what?
Ca2+ VGIC to close, so intracellular Ca2+ concentrations fall
Low levels of intracellular Ca2+ levels in photoreceptors causes what?
Less glutamate to be released by exocytosis to bipolar cells