Sem 1 - F - Anterior & middle (of inferior) mediastinum - external/internal features, shape, blood supply, valves, innervation Flashcards

1
Q

The thoracic cavity is split into the right hemithorax, the left hemithorax and the mediastinum The mediastinum can be split into superior and inferior mediastinum What is the line drawn that splits the mediastinum?

A

This would be a line drawn from the sternal angle posteriorly to the T4/5 intervertebral disc - this line is known as the transverse thoracic plane

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2
Q

What are the boundaries of the superior mediastinum?

A

Superiorly - thoracic inlet Inferiorly - transverse thoracic plane (runs from sternal angle to T4/5 IV disc) Anteriorly - manubrium Posteriorly - Bodies of T1-4 vertebrae Laterally - Pleura of lungs

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3
Q

What can the inferior mediastinum be split into? What structure does the separations of the inferior mediastinum depend upon?

A

Inferior mediastinum can be split into the anterior, middle and posterior Anterior = anterior to the fibrous pericardium Middle - within the fibrous pericardium Posterior - posterior to the fibrous pericardium

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4
Q

What are the boundaries of the anterior inferior mediastinum? (remember, will have a superior, inferior, anterior and posterior boundary)

A

Transverse thoracic pane superiorly Diaphargm inferiorly Body of sternum anteriorly Fibrous pericardium posteriorly

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5
Q

What are the contents of the anterior inferior mediastinum? Which structure is only present here in children?

A

Contents

Loose connective tissue Fat Lymphatics In children the thymus is also present in the anterior inferior mediastinum however this primary lymphoid organ has become fat in the superior mediastinum by the time adulthood is reached

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6
Q

What are the contents of the middle inferior mediastinum and what are the adjacent structures?

A

Contents Heart and pericardium Roots of the great vessels - aorta, pulmonary trunk, superior vena cava Adjacent structures * Great vessels * Phrenic nerve * Lung root structures

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7
Q

Is the fat covering the fibrous pericardium in the anterior or middle aspect of the inferior mediastinum?

A

The fat is in the anterior aspect of the inferior mediastinum

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8
Q

What proportion of the heart is to the right and left of the midsternal line? What is the nerve roots of the phrenic nerve and what does the phrenic nerve supply?

A

1/3rd of the heart is to right of the midsternal line 2/3rds of the heart is to the left of the midsternal line Phrenic nerve - C3,4,5 - supplies motor fibres to diaphragm, sensory fibres to fibrous pericardium, mediastinal pleura, diaphragmatic peritoneum

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9
Q

Where does the phrenic nerve pass in relation to the hilum of the lung? Where does the phrenic nerve pass in relation to the chambers of the heart?

A

Both right and left phrenic nerves pass anteriorly to the hilum of the lung Right phrenic nerve passes on the pericardium over the right atrium Left phrenic nerve passes on the pericardium over the left atrium and left and ventricle

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10
Q

What does the fibrous pericardium blend with superiorly and inferiorly?

A

Superiorly - the fibrous pericardium blends with the tunica adventitia of the great vessels (pulmonary trunk, aorta, superior vena cava) Inferiorly - the fibrous pericardium is continous with the central tendon of the diaphragm

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11
Q

Deep to fibrous pericardium is the serous pericardium divided into what? What is often under the deeper layer of serous pericardium?

A

The serous pericardium is divided in the serous visceral and serous parietal pericardium The serous visceral pericaridum is the deeper layer actually sitting on the heart itself and often has a fatty layer deep to it on the surface of the heart

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12
Q

State the arrangement of the pericardium all the way from the fibrous pericardium to the thin layer that lines the chambers of the heart? What is another name for the serous visceral pericardium?

A

Fibrous pericardium Serous parietal pericardium Pericardial cavity Serous visceral pericardium (also known as the epicardium) Myocardium Endocardium - thin surface lining of the chambers of the heart

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13
Q

Parietal pericardium reflected over the heart as visceral pericardium aka epicardium (outer layer of the heart) In the serous pericardium there are different sinuses formed by the reflections of the serous pericardium over the vessels exiting/entering the heart What are these two sinuses known as?

A

These are the oblique and the transverse sinus It is due to the way in which the parietal pericardium is reflected on to the heart as visceral pericardium

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14
Q

Where i the transverse pericardial sinus?

A

The transverse pericardial sinus runs posterior to the pulmonary trunk and ascending aorta and anterior to the superior vena cava - if sticking a finger in this sinus, it would allow one to separate the arteries and veins

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15
Q

Where is the oblique pericardial sinus and how is it formed? What sits anterior to the oblique pericardial sinus?

A

The oblique pericardal sinus is formed by the reflection of the serous parietal pericardium onto the pulmonary veins of the heart The oblique pericardial sinus runs in the space underneath and beind the heart between the IVC and 4 pulmonary veins Anterir to the oblqiue pericardial sinus is the left atrium

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16
Q

Transverse pericardial sinus - separates arteries of great vessels from veins - posterior to aorta and pulmonary trunk, anterior to SVC Oblique pericardial sinus - formed by reflection on the pulmonary veins - between IVC and pulmonary veins What shape is the heart said to be? What shape are the lungs said to be?

A

The heart is said to be trapezoidal shaped The lungs are said to be pyramidal shaped

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17
Q

Important to know the shape and orientation of the heart As said the heart is trapezoidal in shape The heart has a base, right border, inferior border, apex, left border and superior border Where is the base of the heart and what forms it?

A

The base of the heart is posterior and is mainly the left atrium

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18
Q

What makes up the different borders of the heart? * Right border * Inferior border * Apex * Left border * Superior border

A

Right border - right atrium Inferior border - right ventricle Apex - left ventricle Left border - left ventricle and left auricle Superior border - right and left atria and auricles

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19
Q

Bit that sticks out from the right atrium is the right auricle – just an expansion from the right atrium Which part of the left atrium is seen on the anterior surface of the heart? Where is the left atrium of the heart?

A

The left auricle is the part of the left atrium able to be seen on the anterior surface of the heart The left atrium is at the base of the heart (posterior)

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20
Q

There a number of indentations on the surface of the heart Which groove separates the atria from the ventricles (both names)? Which groove separates the ventricles of the heart?

A

The atrioventricular grooves separate the atria and ventricles of the heart - also known as coronary grooves as the coronary arteries run in these grooves The anterior and posterior interventicular grooves separate the ventricles of the heart

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21
Q

Which great vessel leaves the right ventricle? What does it split into? Which great vessel leaves the left ventricle? What does it branch into? Which great vessels enter the right atrium?

A

Pulmonary trunk leaves the right ventricle before bifurcating into right and left pulmonary arteries The aorta leaves the left ventricle a the ascending aorta and at the arch of the aorta gives off three branches, from right to left, brachiocephalic trunk, left common carotid artery, left subclavian artery Superior and inferior vena cava enter the right atrium

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22
Q

What are the circles covering here? (they are covering the vessels which the arows are pointing to?

A

The right and left coronary arteries running

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23
Q

What is the fibrous remnant of the ductus arteriosus known as? What was its function during foetal life? Where does it lie?

A

The fibrous remnant of the ductus arteriosus is the ligamentum arteriosum During foetal life its function was to allow communication between the pulmonary trunk and aorta therefore bypassing the foetus’s fluid filled lungs It lies just after the three vessels on the inferior surface of the arch of the aorta

24
Q

What nerve runs posterior to the ligamentum arteriosum?

A

The left recurrent laryngeal nerve loops around the arch of the aorta posterior to the ligamentum arteriosum in the adult an back up to the neck

25
Q

The left recurrent laryngeal nerve enters the mediastinum (superior mediastinum), does the right recurrent laryngeal nerve enter the mediastinum?

A

Right recurrent laryngeal nerve does not enter the mediasitnum as it arches around the right subclavian artery which is more of a structure in the neck

26
Q

Heart has a profuse arertial supply from two main branches coming directly from the base of the ascending aorta What are these two main branches?

A

These would be the right and left coronary arteries

27
Q

Right coronary artery wil run in the right atrioventricular groove, just before heading to the inferior surface of the heart gives off a named branch What is this named branch known as? What is the terminal branch of the right cornoary artey posterioryl?

A

Just before the inferior border of the heart, the RCA gives off the right marginal artery The terminal branch of the RCA is the posterior interventricular artery

28
Q

The right cornoary artery as stated gives off the right marginal artery and posterior interventricular artery What other two branches come from the RCA? What in total does the RCA supply?

A

* Right marginal artery * Posterior interventricular artery * SA nodal branch * AV nodal branch Supplies: * Right atrium and most of right ventricle * SA and AV node * Posterior 1/3rd of the IV septum * Part of the left ventricle

29
Q

Left coronary artery in contrast to the RCA is very short What does the left cornoary artery branch into very quickly?

A

Branches into the the circumflex and anterior interventricular artery

30
Q

What is the anterior interventricular artery also known as? What branch does the anterior interventricular artery give off that heads towards the apex of the heart? What does the circumflex artery run in?

A

Anterior interventricular artery aka left anterior descending (LAD) Gives off the diagonal branch which heads towards the apex of the heart The circumflex artery runs in the left atrioventricular groove

31
Q

What branch does the circumflex artery give and what branches can it give (human variation)?

A

Circumflex artery gives off the left marginal artery before going to the posterior aspect of the heart in the atrioventricular groove Sometimes gives of a SA node and posterior inteventricular artery branch

32
Q

State in total the branches from the RCA and LCA arteries

A

RCA * Sa nodal branch * AV nodal branch * Right marginal artery * Posterior interventricular artery LCA Circumflex artery - left marginal artery, can give SA nodal and posterior interventricular branches Anterior interventricular artery (left anterior descending) - diagonal branch

33
Q

Right coronary artery supplies: * R. atrium and most of R. ventricle * SA (usually) and AV nodes * Posterior 1/3 of IV septum * Part of L. ventricle What does the left coronary artery supply?

A

Left atrium and most of left ventricle Anterior 2/3rds of IV septum AV bundle Part of the right ventricle

34
Q

Where do all the veins draining the heart drain to? There is one exception

A

All veins draining the heart technically drain into the coronary sinus which in turn drains into the right atrium of the heart The exception is the anterior cardiac veins which drains the wall of the right atrium directly into the right atrium

35
Q

What veins drain into the right atrium?

A

Superior vena cava Inferior vena cava Coronary sinus Anterior cardiac veins

36
Q

Veins of the heart * Great cardiac vein * Middle cardiac vein * Small cardiac vein What are these three veins’ equivalent? (ie which arteries do they run alongside) What are the other veins which drain into the coronary sinus? Remember, anterior cardiac veins drain the wall of the right atrium directly into the right atrium

A

Great cardiac vein - anterior interventricular artery Middle cardiac vein - posterior interventricular artery Small cardiac vein - right marginal artery Also have the Left marginal vein Left posterior ventricular vein Oblique vein of left atrium

37
Q

What is the main tributary vein to the coronary sinus? State all the veins emptying into the coronary sinus?

A

The great cardiac vein is the main tributary to the coronary sinus * Great cardiac vein * Middle cardiac vein * Small cardiac vein * Left posterior ventricular vein * Oblique vein of the left atrium * Left marginal vein

38
Q

Within the RA, a number of dinstinctive features If you reflect the anterior wall of the RA, it has numerous muscular ridges What are these muscular ridges known as? The posterior wall of the right atrium is very smooth, what is it known as?

A

The muscular ridges in the anterior wall of the right atrium is the musculi pectinati (pectinate muscles) The smooth posterior wall of the right atrium is known as the sinus venarum (origin comes form venous structures)

39
Q

What structure separates the smooth posterior wlal of the right atrium and the muscular anterior wall of the right atrium? What lies in the upper wall of this very pronounced structure?

A

The crista terminalis is the very pronounced ridge separating anterior muscula wall from posterior smooth wall In the upper wall of the crista terminalis is the SA node, near the opening of the SVC

40
Q

In the wall of the RA separating it from the LA is the fossa ovalis What is this structure? WHat ae the muscular ridges in the anterior walls of the auricles/atria known as? What is the smooth posteiror wall of the RA known as?

A

Fossa ovalis - remnant of foramen ovale - used to connect the RA to LA to avoid unoxygenated blood going to the fluid filled feotal lungs Muscular ridges in anterior walls - musculi pectinati Smooth posterior wall of RA - sinus venarum

41
Q

Within the right ventricle there are bigger muscular ridges What are these ridges known as?

A

Known as the trabeculae carnae

42
Q

Sticking out from the muscular walls are the papillary muscles What do these attach to, to attach to what?

A

The papillary muscles attach to the trabecular carnea of the ventricles, and then attach chordae tendinae to the valves separating the RA from RV

43
Q

What is the valve separating the RA from RV known as? What is the band unique to the right ventricle conducting system known as? Where does it attach?

A

Valve - the tricuspid valve (right atrioventricular valve) Band unique to RV conducting system - moderator band Attaches from IV septum to the anterior papillary muscles

44
Q

What is the other name for the moderator band?

A

The moderator band is also known as the septomarginal trabecular (termed moderator band as it was originally believed to prevent over expansion of ventricle)

45
Q

What is the function of the moderator band?

A

Provides a shortcut for electrical activity in the right ventricle so it does not have to descend down the right bundle branch blocks to purkinje fibres Allows a primary conduction route from the right AV bundle branch block to the anterior papillary muscles of heart causing them to contract

46
Q

What are the muscular ridges of the LA and LV also known as? Which specific part of the left atrium actually has muscular ridges? What separates the LA from the LV?

A

The left atrium is mostly smooth walled, it is only the left auricle whih is muscula - the muscular ridges are known as musculi pectinati LV - trabeculae carnae This would be the bicuspid valve (Mitral valve)

47
Q

Describe the blood flow of the cardiovascular system

A

Blood enters RA from SVC, IVC, Anterior cardiac veins, coronary sinus Ra - RV - pulmonary trunk then right and left pulmonary arteries into the respective lungs Blood is oxygenated in the lungs From lungs to pulmonary veins to LA - LV then to aorta Descending aorta , arch of aorta to the head/neck/ upper limb and the en to descending aorta for rest of the body

48
Q

At the base of the aorta and the pulmonary trunk have two similar valves – the semilunar valves When the ventricles contract, blood will force the valves open due to an increase in pressure forcing blood into aorta and pulmonary trunk What happens to the valves when the ventricles relax?

A

When the ventricles relax, there will be a backflow of blood into the ventricles due to gravity Some of the blood will collect in the space between the leaflets of the semilunar valves and the vessel wall and this forces the valve to shut

49
Q

How does the backflow of blood into the space between semilunar valves leaflets and vessel walls effect the coronary arteries?

A

The coronary arteries come off the ascending aorta adjacent to where the semilunar valves are located, therefore when there is the backflow of blood, this will close the valves and drain blood into the coronary arteries to supply the myocardium of the heart

50
Q

Cuspid valves operate essentially on opposite principles from the semilunar valves Valves are open when there is low pressure in the ventricle When do the tricuspid (left) and bicuspid/mitral (right) valves close?

A

Pressure in the ventricles increases, the pressure in the atrium will decrease & cuspid valves will close The huge spike in pressure due to the ventricle contraction will also cause the papillary muscles to contract meaning the chordae tendinae will become taught preventing the valves opening

51
Q

What is the difference in the valves during diastole and systole?

A

During diastole, the ventricles are relaxed and therefore the cuspid valves are open (pressure in atria is greater) & the semilunar valves are closed (coronary arteries fill) During systole, the ventricles are contracted meaning the cuspid valves are closed and the semilunar valves are open

52
Q

The fibrous skeleton of the heart provides electrical insulation between atria and ventricles and support for the valves Which aspect provides electrical insulation between atria and ventricles? What does this allow?

A

The Membranous atrioventricular septum provides electrical insulation between atria and ventricle which means they do not both depolarise at the same time

53
Q

What aspects of the fibrous skeleton provide support for the valves?

A

Left fibrous ring (supports mitral valve) Right fibrous ring (supports tricuspid valve) Fibrous coronet of pulmonary valve (supports pulmonary valve) Fibrous coronet of aortic valve (supports aortic valve)

54
Q

Heart muscles cells left to their own devices will depolarise and contract but slowly The SA node ensures that this depolarisation and contraction occurs smoothly – it is the pacemaker for the heart regulating the heart rate * The SA node will spread from the RA to LA as well * The SA node recieves additional input from the ANS What in in the ANS helps innervate the heart? (where is the ganglia)

A

Heart recieves parasympathetic innervation from the Vagus nerve (X) - intrinsic ganglia Sympathetic innervation from T1-T5/6 spinal levels - cervical and superior thoracic paravertebral ganglia (sympathetic chain)

55
Q

Where is the cardiac plexus located?

A

The cardiac plexus is located just behind the arch of the aorta