seizure Flashcards
what are the early drugs used for seizures
hydantoins (phenytoin)
barbiturates (phenobarbital)
oxazolidinediones (trimethadone)
succinimides (ethosuximide)
acetylureas (phenacemide)
which drugs prolong na channel inavtication
phenytoin, carbamazaepine, lamotrigine, phenobarbital, topiramate, valproate
which seizures are NA channel actions best for
focal
which drugs target T-type Ca channels
ethosuxamide valproate lamotrigine
how do drugs actt on T-type Ca channels
suppression
which seziures are best treated by T-type suppressors
absence
which drugs act on GABA receptors directly
barbiturates, benzodiazepine, topiramte
which drugs act on GABA receptors indirectly
gabapentin, tiagagine, vigabatrin
which drugs reduce glutamate action
phenobarbital, topiramate
how does phenytoin act
blocks repetitive firing of Na and K
blocks Ca influx
how does carbamazepine act
blocks repetitive firing of Na and K
block Ca influx
which antiseizure drug is chosen in patients < 2 yo & how does it work
phenobarbital, suppresses excitatory, potentiates GABA
how does ethosuxamide work
inhibit T-type Ca
what kind of seizures is ethosuximide good for
absence seizures
what is valproic acid
anti seizure drug for partial, myoclonic, primary GTTC,absence etc
