Autonomic III

Question 1

what are the choline esters of interest

Answer 1

acetylcholine, carbochol, bethanechol, methacholine

Question 2

how are choline esters abosrbed in GI tract

Answer 2

poorly

Question 3

name whether the following are nicotinic or muscarinic
ACh
carbachol
bathanechol

Answer 3

ACh - nic and musc
carbachol - nic and musc
bethanechol - musc

Question 4

what are the muscarinic agonists

Answer 4

muscarine, oxetromorine, pilocarpine

Question 5

how do muscaniric agonists affect the bladder

Answer 5

stimulate detrusor muscle, relax trigone and internal sphincter promotes voiding

Question 6

how does nicotine behave in the cardiovascular regions

Answer 6

sympathetic

Question 7

how does nicotine affect GI

Answer 7

parasympathetic

Question 8

what are anticholinesterases

Answer 8

indirectly stimulate nicotinic and muscarinic receptors by preventing hydrolysis of ACh

Question 9

what is the simple alcohol anticholinesterase

Answer 9

edrophonium

Question 10

what is the carbamic ester of alcohol that is an anticholinesterase

Answer 10

neostigmine

Question 11

what is the organophosphate anticholinesterases (2)

Answer 11

malathion, soman

Question 12

what are the therapeutic uses of cholinomimetics

Answer 12

glaucoma
urinary retention

Question 13

what is the cholinergic nicotinic antagonist used in surgery

Answer 13

succinylcholine

Question 14

what is the prototypic drug for succinylcholine

Answer 14

D-tubocurarine

Question 15

what is alpha-bungarotoxin

Answer 15

nicotinic antagonist

Question 16

what is the main muscarinic antagonist

Answer 16

atropine

Question 17

what drug can be used to cure motion sickness

Answer 17

scopolamine

Question 18

what drug is used for COPD
what kind of drug is it

Answer 18

ipratropium
muscaniric antagonist

Question 19

what are the 3 directly acting sympathomimetics

Answer 19

adrenaline, noradrenaline, isoproterenol

Question 20

what are alpha1 adrenoceptors blocked by

Answer 20

PRAZOSIN