Autonomic IV Flashcards
how do alpha1 and beta2 receptors act differently in blood vessels
alpha 1 = vasoconstriction, increased arteriolar restriction, increased BP
beta2 = smooth muscle relaxation, vasodilation, decreased peripheral resistance, reduced BP
what kind of receptors are mostly found on skin and spleen blood vessels
alpha 1 `
blood vessels in muscles contain which receptors
both alpha1 and beta 2
dilated or constricted depending
how do presynaptic alpha2 vs presynaptic beta differ
alpha = decrease NA
beta = increase NA
which beta receptors are found on presynaptic terminals
both 1 & 2
which alpha receptors are found on presynpatic terminals
alpha 2
what is phenylephrine
alpha agonist
what results do pure alpha agonists produce
increased BP but decreased HR
how do pure beta agonists affect the cardio system
fall in BP, rise in HR
what is an example of a pure beta agonist
isoproterenol
how could an alpha and beta agonist affect the cardio system and why
increased HR (due to BETA1)
vasoconstriction (initially) until beta2 is stimulated in muscle blood vessels
what is mydriasis
widening of iris
what kind of receptors are in nasal blood vessels
alpha
how does alpha 2 agonists indirectly relac the GI
decreased release of ACh
how do alpha2 and beta2 function differently in the endocrine system
alpha2 = inhibition of insulin and renin release
beta2 = stimulation of insulin and renin release
what are the metabolic affects of adrenoceptors
Beta3 in fat cells promote lypolys
beta receptors in liver promote glycogenolysis
what does adrenalic stimulate
cardiac
how does adrenaline act in skeletal blood vessels at each receptor
alpha vasoconstrictor
beta2 vasodilator
how does tyramine affect catecholamine release
induces release
how does isoproterenol act
cardiac stimulant, beta 1 effects
vasodilator beta 2 effect
which receptors is dobutamine selective for
beta 1
which receptors is salbutamol selective for
beta 2
what kind of agonist is phenylephrine
alpha
what is phentolamines mechanism of action
alpha1 and alpha 2 blocker
