Seibert - Disorders of the Vulva, Vagina, Cervix Flashcards
commonly seen conditions of the vulva
lichen sclerosis
lichen simplex chronicus
lichen planus
mc non-neoplastic vulvar epithelial d.o
lichen sclerosus
intense vulvar pruritis usually in women > 60 yo
lichen sclerosus
what is this
lichen sclerosus
benign epithelial thickening and hyperkeratosis resulting from chronic irritation
lichen simplex chronicus
which type of lichen needs bx to r.o cancer
lichen simplex chronicus
what is this
lichen simplex chronicus
inflammatory AI lichen
lichen planus
tx for the lichens
steroids
what do you think when you see: recurrent oral ulcers, recurrent genital aphthae/ulcerations, and uveitis
bechet’s syndrome triad
what is this
bachet’s
sexually transmitted conditions
pediculosis pubis
condyloma acuminatum
HSV
molluscum contagiosum
crab louse transmitted through sexual contact or shared infected bedding or clothing
pediculosis pubis
std that has distinctly verrucous lesions and involves asymptomatic papillary growths
condyloma acuminatum
condyloma acuminatum is caused by
HPV
what do you think when you see vesicles that erode rapidly resulting in painful ulcer, surrounded by red halo
HSV
main complication of HSV
transmission to neonate during birth
prodrome of HSV mimics
flu
(covid)
benign epithelial poxvirus that is dome shaped w. a typical umbilicus; typically not itchy
molluscum contagiosum
molluscum contagiosum is usually seen in __
but can also be __
kids
sexually transmitted
what is this
molluscum contagiousum
fleshy warts
in adults, molluscum contagiosum is considered
STI
obstruction of main duct of bartholin gland
bartholin duct cyst and abscess
fxn of bartholin gland
moisturize vulva/vagina → obstruction causes cyst/abscess
sx of bartholin cyst/abscess
pain
tendernes
dyspareunia
difficult walking
what is this
bartholin gland cyst
tx for bartholin gland cyst
I&D
catheter placement
marsupialization
atrophy 2/2 diminished estrogen levels; mc in post-menopausal women; pH of vagina abnormally high
atrophic vaginitis
tx for atrophic vaginitis
supplemental estrogen therapy
if no contraindications
topical estrogens
premarin
estrace
vagifem
90% of vulvar malignancy is
squamous cell carcinoma
what might you see on the hx of a pt w. vulvar malignancy
lichen sclerosis
Bachet’s
rf for vulvar malignancy
smoking cigs
HPV
immunodeficiency
hx cervical carcinoma
chronic vulvar irritation
vulvar malignancy is sensitive to
chemo
in situ adenocarcinoma in epithelium of vulva and perianal regions
paget dz of the vulva
itchy, red crusted lesions usually on labia majora; +/- superficial white coating, “cake icing”
paget dz of vulva
tx for paget dz of the vulva
refer to gyn
bx
normal vaginal environment is
acidic
lots of vaginal flora
how should the vagina be cleaned
it is a self cleaning system!!
mc reason for pt visits to gynecology offices
vulvovaginitis
mc causes of vulvovaginitis
bacterial vaginosis (BV)
trichomoniasis
candidiasis
can be associated w. all 3
which of the 3 causes of vulvovaginitis is considered an STI
trichomoniasis
bv is caused by
gardnerella vaginalis
vaginal candidiasis is caused by
c albicans
what promotes c. albicans infxn (4)
systemic abx
DM
pregnancy
OCP
what do you think when you see: motile, pear-shaped flagellated cells and strawberry cervix
trichomoniasis vulvovaginitis
5 tests for vulvovaginosis
vaginal pH
amine whiff test
KOH
saline (wet prep)
DNA of gardnerella vaginalis, trichomonas vaginalis
if a non sexually active pt presents w. a yeast infxn that you determine to be candidiasis, do you need to test for chlamydia/gonorrhea
no!
candidiasis is not an STI
90% of vulvovaginal candidiasis is caused by
candidia albicans
what do you think when you see: itching, white vaginal discharge, vulvar erythema, high pH, odorless
vulvogainal candidiasis
gold standard dx for vulvovaginal candidiasis
vaginal culture
branching pseudohyphae and spores; spaghetti and meatballs
KOH finding for vulvovaginal candidiasis
tx for vaginal candidiasis
creams, suppositories, oral:
fluconazole
clotrimazole
miconazole
nystatin
for dx of BV you need 3 out of what 4 criteria
abnormal gray discharge
pH > 4.5
(+) whiff test
presence of clue cells
thin gray-white to yellow discharge
gardnerella vaginitis
ground glass appearance
clue cells → BV
tx for bv
metronidazole
clindamycin
tx for pregnant pt w. BV
metronidazole
flagellate protozoan that lives in vagina, skene ducts, and male or female urethra
trichomonas vaginitis
what do you think when you see: vulvar itching, burning, copious discharge w. odor, dysuria, dyspareunia
trichomonas vaginitis
thin, frothy discharge, foul smelling, yellow-green, pH > 5, strawberry cervix
trichomonas vaginitis
dx for trichomonas vaginitis
wet-mount prep
tx for trichomonas vaginitis
systemic metronidazole
thick, frothy, foul flagellates
trichomonas
grey, pH, whiff, clue
BV
itchy, white, adherent, no odor
candidiasis/yeast
what do you think when you see: abnormal malodorous vaginal discharge, intramenstrual bleeding
foreign bodies
retained tampons usually cause
ulcerative lesions
toxic shock syndrome is caused by what pathogen
staph vaginal infxn
when would you use abx for foreign body
cellulitis
systemic sx → fever
recommendation for tampons
least absorption for the least amount of time
sx of TSS are similar to flu, how do you differentiate
menstruating woman who uses tampons
BP changes
rash
any menstruating woman presenting w. sudden onset of febrile illness should be evaluated and treated for
TSS
tx for TSS
remove tampon
vaginal cultures
copious irrigation
b-lactamase resistant PCN or vano
can patients who have had TSS use tampons again
no! → high risk to get it again
inflammatory disorder of the upper genital tract that is a serious cause of morbility, mortality, and infertility
PID
PID is often caused by
n. gonorrhea
PID can also be caused by
c trachomatis
anaerobes
PID can easily be confused with
TSS
acute appendicitis
6 rf for PID
< 25 yo
previous PID
untreated STI
multiple sex partners
douching
IUD
what can be a unique sx of PID (2)
irregular vaginal bleeding
cervical motion tenderness
vague sx of PID
abd pain
fever
vaginal/cervical d.c
pain or bleeding w. intercourse
minimum criteria for PID dx
cervical motion tenderness
OR
uterine motion tenderness
OR
adnexal tenderness
PLUS
fever, cervical d.c, elevated ESR/CRP, documented cervical infxn
should you wait confirm PID dx before treating it to
no!
tx for PID
ceftriaxone IM PLUS doxycycline
+/- metronidazole
all tx protocols for PID must treat
gonorrhea
chlamydia
education regarding sexual intercourse during PID tx
avoid intercourse for entire tx course
you must do a __ on all patients w. suspected PID
pelvic exam
85% of malignant diseases of the vagina are
squamous cell cancers
what is DES
diethylstilbestrol → synthetic nonsteroidal estrogen
increases risk for vaginal clear cell carcinoma and other GU tract abnormalities in utero
what is a cystocele
bladder prolapse
what is a cystourethrocele
bladder and urethra prolapse together
eversion of columnar epithelium onto ectocervix; cervix appears red, granular, inflamed
ectropion
ectropion is benign and associated w. __ (2)
but needs __
hormone changes → pregnancy/puberty
cervical ca work up
very common, typically asymptomatic translucent-yellow mucous-filled cyst on the surface of the cervix
nabothian cyst
cervicitis indicates
spread of vaginal infxn
major concern w. cervicitis
infxn will spread and cause PID
2 major sign of cervicitis
cervical friability →
spotting
post coital bleeding
major sx of chronic cervicitis
leukorrhea
major cause of amenorrhea
cervical stenosis
condition that occurs when weak cervical tissue causes or contributes to premature birth or the loss of an otherwise healthy pregnancy
incompetent cervix
tx for incompetent cervix
cervical cerclage
progesterone
if you ever have a doubt about a diagnosis, you should
refer!
think __
treat __
save __
infection
infection
fertility