Dobbs - Uterine Disorders Flashcards
regular interval btw menses, excessive flow and duration
menorrhagia
decreased flow during normal duration of regular menses
hypomenorrhea
metorrhagia
irregular interval of menses, excessive flow and duration
shortened interval btw menses < 9-21 days
polymenorrhea
irregular or excessive bleeding during menses and btw menses
menomotorrhagia
lengthened interval btw menses > 35 day intervals
oligomenorrhea
procedure to remove tissue from inside the uterus
dilation and curettage (D&C)
D&C is used to dx and treat (2)
heavy bleeding
clear uterine lining after miscarriage/abortion
pain associated w. menses
1-2 days of mild discomfort-severe pain everyday of menses
dysmenorrhea
sx associated w. dysmenorrhea (3)
n.v
fatigue
diarrhea
what causes dysmenorrhea
prostaglandin overactivity
tx for dysmenorrhea (4)
NSAIDs
heat
avoid nicotine, etoh, caffeine
reduce frequency of menses
persistent dysmenorrhea → r.o (3)
leiomyomas
endometriosis
ovarian cysts
common benign uterine tumor
round, firm, often multiple; composed of smooth m/CT
leiomyoma (same-same uterine fibroid)
fibroids depend on
estrogen
fibroids are classified by
location
uterine fibroids may be asymptomatic; name 4 sx if not
bleeding → MC
pressure or fullness in pelvis
menorrhagia, metorrhagia, intermenstrual bleeding, dysmenorrhea
anemia w. heavy bleeding
during bimanual exam, you feel firm, enlarged, irregular uterine mass; what do you think
uterine fibroid
mc dx for uterine fibroid
US
other dx options for fibroids (4)
saline hysteroscopy
hysterosalpingography
laparascopy → large fibroids
MRI/CT
tx for asymptomatic fibroids
obs
tx for symptomatic fibroids (3)
myomectomy or D&C
uterine arterial embolization or endometrial ablation
hysterectomy
pharm for uterine fibroids
GnRH agonists (Lupron)
transexamic acid → non hormonal; eases heavy periods
s.e of Lupron
medical menopause → sweats, mood disturbance, sleep disturbance, feel awful
major consideration pre uterine arterial embolization/endometrial ablation
no desire for future fertility
condition where endometrial tissue is found outside of endometrial cavity
endometriosis
4 locations for endometriosis
ovaries
uterosacral ligament
GI tract
lungs/brain → uncommon
definitive dx for endometriosis
have to visualize it (surgically/histologically)
when you see pt w. infertility, think
endometriosis
infertility in endometriosis is related to
adhesions
chocolate cysts on ovaries
endometriosis
insertions filled w. blood
rf for endometriosis (5)
family hx
early menarche
long duration of menstrual flow
heavy bleeding during menses
shorter menstrual cycles
decreased risk for endometriosis (3)
4 or more hr exercise/week
higher parity
longer duration of lactation
US for endometriosis is used to
r. o other conditions
* only way to dx endometriosis is to see it surgically*
3 d’s of endometriosis
dysmenorrhea
dyspareunia
dyschezia
also infertility!!!
what is dyschezia
pain during defecation
tender nodules in posterior vagainal fornix
pain w. uterine motion
tender adnexal masses
clinical findings for endometriosis
repetitive, but probs will be a questions on exam:
dx for endometriosis
direct visualization of implants during laparoscopy or laparotomy PLUS tissue bx
tx fo endometriosis
obs
NSAIDs
surgery
pharm for endometriosis
OCP
IUD
progresterone therapy (Depo Provera, Mirena)
danazol
GnRH (Lupron)
endometrial tissue from uterus exists w.in and grows into the muscular wall of the uterus
adenomyosis
symmetrically enlarged uterus
adenomyosis
sx of adenomyosis if not asymptomatic
severe dysmenorrhea
abd pressure/bloating
heavy bleeding
what do you think when you see: middle aged woman, severe dysmenorrhea, hx of childbearing, symmetrically enlarged uterus, menorrhagia
adenomyosis
definitive dx for adenomyosis
hysterectomy
also pelvic US, MRI
tx for adenomyosis
NSAIDs
hormones
hysterectomy
2 types of pelvic organ prolapse
anterior vaginal wall
posterior vaginal wall
types of anterior pelvic organ prolapse
cystocele
cystourethrocele
types of posterior pelvic organ prolapse
rectocele
enterocele
mc type of pelvic organ prolapse
cystourethrocele
rf for uterine prolapse
post pregnancy/labor
vaginal delivery
post menopause
increased intra-abd pressure
smoking
sx of uterine prolapse are worse after __
and relieved by __
prolonged sitting
lying down
sx of uterine prolapse
vaginal fullness
urinary sx
lower abd pain
low back pain
“falling out sensation”
management of uterine prolapse requires
gyn referral!
non surgical management of uterine prolapse
wt reduction
smoking cessation
pelvic m exercises
vaginal pessary
abnormal menstrual bleeding and bleeding dt other causes (pregnancy, systemic dz, cancer)
abnormal uterine bleeding (AUB)
mc cause of AUB
pregnancy
exclusion of all possible pathologic causes of AUB establishes dx of
dysfunctional uterine bleeding (DUB)
AUB includes (5)
bleeding btw periods
bleeding after intercourse
spotting any time after menstrual cycle
bleeding heavier or for more days than normal
bleeding after menopause
causes of AUB (many!!)
PCOS
pregnancy
miscarriage
ectopic pregnancy
adenomyosis
birth control
hormones
STIs
fibroids
clotting d.o
polyps
endometrial hyperplasia
cancer
4 structural causes of AUB
PALM
polyp
adenomyosis
leiomyoma
malignancy/hyperplasia
5 nonstructural causes of AUB
coine
coagulopathy
ovarian dysfxn
iatrogenic
not yet classified
endometrial process
evaluation of AUB depends on
age → hormonal flow
ex have they had first period? vs menopause
2 exams that is especially important for evaluation of AUB
rectovaginal → palpate uterus
cytological → pap smear
mc cause of AUB
iatrogenic
gold standard eval tool for AUB
hysteroscopy → direct visualization of endometrium
other important imaging for AUB (2)
pelvic US
endometrial bx
tx to try for AUB
progesterone
OCP
surgical
bleeding that occurs after 12 months of amenorrhea in a middle-aged woman
postmenopausal bleeding
2 lab values highly suggestive of menopause
FSH > 30 miUL/mL
estradiol < 20
mc cause of postmenopausal bleeding
use of exogenous hormones
mc gyn cancer
endometrial
mc type of endometrial ca
adenocarcinoma
rf for endometrial ca
increasing age
obesity
nulliparity/infertility
late menopause
early menarche
DM
unopposed estrogen
genetic predisposition
prior pelvic xrt
cardinal sx of endometrial ca
abnormal uterine bleeding
other sx of endometrial ca
abnormal vaginal d.c
intermittent spotting
lower abd cramps/pain
dx for endometrial ca
incidental on pap
pelvic US
D&C
endometrial bx
tx for endometrial ca
gyn referral!
total hysterectomy w. salpingo-oophrectomy
xrt
chemo
basis of tx and staging for endometrial ca
total hysterectomy w. combined oophrectomy