Secretory Pathway Flashcards

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1
Q

Many secreted proteins are synthesised as

A

inactive precursors and require proteolytic cleavage to produce active proteins

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2
Q

Examples of secreted proteins?

A

peptide hormones and digestive enzymes

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3
Q

The secretory pathway 1

A

Secreted proteins are translated in ribosomes on the RER and enter its lumen.

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4
Q

The secretory pathway 2

A

The proteins move through the Golgi apparatus and are then packaged into secretory vesicles

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5
Q

The secretory pathway 3

A

These vesicles move to and fuse with the plasma membrane, releasing the proteins out of the cell

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