Seafood Flashcards
What is the source of Tetrodotoxin?
Pufferfish (fugu)
What is the mechanism of action of Tetrodotoxin?
Blocks voltage-gated sodium channels
What are the symptoms of Tetrodotoxin poisoning?
Tingling
What is the source of Saxitoxin?
Shellfish (e.g.
What is the mechanism of action of Saxitoxin?
Blocks voltage-gated sodium channels
What are the symptoms of Saxitoxin poisoning?
Paralysis
What is the source of Ciguatoxin?
Reef fish (e.g.
What is the mechanism of action of Ciguatoxin?
Opens voltage-gated sodium channels (persistent depolarization)
What are the symptoms of Ciguatoxin poisoning?
Nausea
What is the source of Paralytic shellfish poison (PSP)?
Shellfish (e.g.
What is the mechanism of action of Paralytic shellfish poison (PSP)?
Blocks voltage-gated sodium channels
What are the symptoms of Paralytic shellfish poison (PSP) poisoning?
Nausea
What is the source of Domoic acid?
Shellfish (e.g.
What is the mechanism of action of Domoic acid?
Activates glutamate receptors (neurotoxicity)
What are the symptoms of Domoic acid poisoning?
Nausea
What is the source of Scombroid poisoning?
Spoiled fish (e.g.
What is the mechanism of action of Scombroid poisoning?
Histamine release due to bacterial breakdown of histidine
What are the symptoms of Scombroid poisoning?
Flushing
What is the source of Brevetoxin?
Dinoflagellates (e.g.
What is the mechanism of action of Brevetoxin?
Opens voltage-gated sodium channels (persistent depolarization)
What are the symptoms of Brevetoxin poisoning?
Nausea
What is the source of Okadaic acid?
Dinoflagellates in contaminated shellfish (e.g.
What is the mechanism of action of Okadaic acid?
Inhibits protein phosphatases
What are the symptoms of Okadaic acid poisoning?
Diarrhea
