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Rapid Rev USMLE 1 > Seafood > Flashcards

Seafood Flashcards

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USMLE® Step 1 flashcards
1
Q

What is the source of Tetrodotoxin?

A

Pufferfish (fugu)

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2
Q

What is the mechanism of action of Tetrodotoxin?

A

Blocks voltage-gated sodium channels

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3
Q

What are the symptoms of Tetrodotoxin poisoning?

A

Tingling

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4
Q

What is the source of Saxitoxin?

A

Shellfish (e.g.

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5
Q

What is the mechanism of action of Saxitoxin?

A

Blocks voltage-gated sodium channels

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6
Q

What are the symptoms of Saxitoxin poisoning?

A

Paralysis

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7
Q

What is the source of Ciguatoxin?

A

Reef fish (e.g.

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8
Q

What is the mechanism of action of Ciguatoxin?

A

Opens voltage-gated sodium channels (persistent depolarization)

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9
Q

What are the symptoms of Ciguatoxin poisoning?

A

Nausea

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10
Q

What is the source of Paralytic shellfish poison (PSP)?

A

Shellfish (e.g.

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11
Q

What is the mechanism of action of Paralytic shellfish poison (PSP)?

A

Blocks voltage-gated sodium channels

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12
Q

What are the symptoms of Paralytic shellfish poison (PSP) poisoning?

A

Nausea

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13
Q

What is the source of Domoic acid?

A

Shellfish (e.g.

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14
Q

What is the mechanism of action of Domoic acid?

A

Activates glutamate receptors (neurotoxicity)

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15
Q

What are the symptoms of Domoic acid poisoning?

A

Nausea

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16
Q

What is the source of Scombroid poisoning?

A

Spoiled fish (e.g.

17
Q

What is the mechanism of action of Scombroid poisoning?

A

Histamine release due to bacterial breakdown of histidine

18
Q

What are the symptoms of Scombroid poisoning?

A

Flushing

19
Q

What is the source of Brevetoxin?

A

Dinoflagellates (e.g.

20
Q

What is the mechanism of action of Brevetoxin?

A

Opens voltage-gated sodium channels (persistent depolarization)

21
Q

What are the symptoms of Brevetoxin poisoning?

A

Nausea

22
Q

What is the source of Okadaic acid?

A

Dinoflagellates in contaminated shellfish (e.g.

23
Q

What is the mechanism of action of Okadaic acid?

A

Inhibits protein phosphatases

24
Q

What are the symptoms of Okadaic acid poisoning?

A

Diarrhea

Rapid Rev USMLE 1 (12 decks)

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