AntiArrthmia Flashcards

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1
Q

Quinidine

A

Class I (IA)

Na+ channel blocker (intermediate)

QT prolongation, torsades de pointes, cinchonism, hypotension

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2
Q

Procainamide

A

Class I (IA)

Na+ channel blocker (intermediate)

QT prolongation, drug-induced lupus erythematosus, torsades de pointes

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3
Q

Disopyramide

A

Class I (IA)

Na+ channel blocker (intermediate)

Anticholinergic effects, heart failure, QT prolongation

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4
Q

Lidocaine

A

Class I (IB)

Na+ channel blocker (fast)

CNS effects (tremor, confusion), hypotension

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5
Q

Mexiletine

A

Class I (IB)

Na+ channel blocker (fast)

CNS effects (dizziness, tremor), gastrointestinal distress

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6
Q

Flecainide

A

Class I (IC)

Na+ channel blocker (slow)

Proarrhythmic effects, blurred vision, dizziness

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7
Q

Propafenone

A

Class I (IC)

Na+ channel blocker (slow)

Proarrhythmic effects, metallic taste, constipation

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8
Q

Propranolol

A

Class II

Beta-adrenergic blocker

Bradycardia, hypotension, bronchospasm, fatigue

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9
Q

Metoprolol

A

Class II

Beta-adrenergic blocker

Bradycardia, hypotension, fatigue, sexual dysfunction

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10
Q

Esmolol

A

Class II

Beta-adrenergic blocker

Bradycardia, hypotension

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11
Q

Amiodarone

A

Class III

K+ channel blocker (also affects Na+, Ca2+, and beta)

Pulmonary fibrosis, thyroid dysfunction, liver toxicity, skin discoloration, QT prolongation

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12
Q

Sotalol

A

Class III

K+ channel blocker, beta-adrenergic blocker

QT prolongation, torsades de pointes, bradycardia

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13
Q

Dofetilide

A

Class III

K+ channel blocker

QT prolongation, torsades de pointes

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14
Q

Ibutilide

A

Class III

K+ channel blocker

QT prolongation, torsades de pointes

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15
Q

Verapamil

A

Class IV

Ca2+ channel blocker

Bradycardia, constipation, hypotension, gingival hyperplasia

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16
Q

Diltiazem

A

Class IV

Ca2+ channel blocker

Bradycardia, hypotension, edema

17
Q

Adenosine

A

N/A

Activates adenosine receptors, hyperpolarizes cells

Transient asystole, flushing, chest pain, dyspnea

18
Q

Digoxin

A

N/A

Inhibits Na+/K+ ATPase, increases vagal tone

Nausea, vomiting, visual disturbances, arrhythmias