AntiArrthmia Flashcards
Quinidine
Class I (IA)
Na+ channel blocker (intermediate)
QT prolongation, torsades de pointes, cinchonism, hypotension
Procainamide
Class I (IA)
Na+ channel blocker (intermediate)
QT prolongation, drug-induced lupus erythematosus, torsades de pointes
Disopyramide
Class I (IA)
Na+ channel blocker (intermediate)
Anticholinergic effects, heart failure, QT prolongation
Lidocaine
Class I (IB)
Na+ channel blocker (fast)
CNS effects (tremor, confusion), hypotension
Mexiletine
Class I (IB)
Na+ channel blocker (fast)
CNS effects (dizziness, tremor), gastrointestinal distress
Flecainide
Class I (IC)
Na+ channel blocker (slow)
Proarrhythmic effects, blurred vision, dizziness
Propafenone
Class I (IC)
Na+ channel blocker (slow)
Proarrhythmic effects, metallic taste, constipation
Propranolol
Class II
Beta-adrenergic blocker
Bradycardia, hypotension, bronchospasm, fatigue
Metoprolol
Class II
Beta-adrenergic blocker
Bradycardia, hypotension, fatigue, sexual dysfunction
Esmolol
Class II
Beta-adrenergic blocker
Bradycardia, hypotension
Amiodarone
Class III
K+ channel blocker (also affects Na+, Ca2+, and beta)
Pulmonary fibrosis, thyroid dysfunction, liver toxicity, skin discoloration, QT prolongation
Sotalol
Class III
K+ channel blocker, beta-adrenergic blocker
QT prolongation, torsades de pointes, bradycardia
Dofetilide
Class III
K+ channel blocker
QT prolongation, torsades de pointes
Ibutilide
Class III
K+ channel blocker
QT prolongation, torsades de pointes
Verapamil
Class IV
Ca2+ channel blocker
Bradycardia, constipation, hypotension, gingival hyperplasia