Screening young adults Flashcards

1
Q

At what age does epidemiology not help at all?

A

50

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2
Q

SCC by age group

A

21-60 - 8%, 61+ 92%

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3
Q

BCC by age group

A

0-20 - 0.2%, 21-60 - 36.8%, 61+ - 63%

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4
Q

Melanoma by age group

A

0-20 - 1%, 21-80 - 57%, 61+ 42%

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5
Q

Melanoma, decades at highest risk

A

40-50, 50-60, 60-70

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6
Q

No. of nevi increase to age …. the decline

A

40

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7
Q

4 main types of nevu

A

globular, reticular, starburst, homegeneous

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8
Q

globular nevi contain nests of melanocytes in the –

A

upper dermis below dermo-epidermal junction

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9
Q

reticular nevus contain melanocytes in the …

A

continuous pigment along dermo-epidermal junction

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10
Q

special categories of nevi

A

hemorrhagic nevus : hemosiderotic targetoid nevus
inflamed nevus
Sclerosing nevus - middle back - white or blue color in middle that looks like regression
Combined nevi

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11
Q

Distinguish combined (blue nevus) from melanoma

A

Blue area with another areas consisting of network and globules - likely benign
Melanoma structureless blue is usually combined with white streaks and usually one other melanoma criterion

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12
Q

Melanoma specific criteria

A
  1. Atypical network
  2. Regression
  3. Irregular dots/ globules
  4. Irregular blotch
  5. Irregular streaks/ pseudopods
  6. Shiny white streaks
  7. Blue/ white veil
  8. Atypical vessels
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13
Q

Additional criterion for early melanoma in situ

A

Irregular Hyperpigmented areas

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14
Q

Fast-growing nodular nevi are most common in patients…

A

Without nevi.

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15
Q

High nevus count confers —— Prognosis in melanoma patients

A

favorable

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16
Q

In Germany they demonstrated …. Less melanoma death from 100,000 patients screened

A

1

17
Q

However in the same study on a long-term follow-up this patient’s had…

A

1 less regional metastases. 4% versus 13%.
2 left distant metastases. 4% versus 8%
3 required less systemic treatment 12% versus 22%
4 experienced survival benefit, hazard ratio 0.4