Screening young adults Flashcards
At what age does epidemiology not help at all?
50
SCC by age group
21-60 - 8%, 61+ 92%
BCC by age group
0-20 - 0.2%, 21-60 - 36.8%, 61+ - 63%
Melanoma by age group
0-20 - 1%, 21-80 - 57%, 61+ 42%
Melanoma, decades at highest risk
40-50, 50-60, 60-70
No. of nevi increase to age …. the decline
40
4 main types of nevu
globular, reticular, starburst, homegeneous
globular nevi contain nests of melanocytes in the –
upper dermis below dermo-epidermal junction
reticular nevus contain melanocytes in the …
continuous pigment along dermo-epidermal junction
special categories of nevi
hemorrhagic nevus : hemosiderotic targetoid nevus
inflamed nevus
Sclerosing nevus - middle back - white or blue color in middle that looks like regression
Combined nevi
Distinguish combined (blue nevus) from melanoma
Blue area with another areas consisting of network and globules - likely benign
Melanoma structureless blue is usually combined with white streaks and usually one other melanoma criterion
Melanoma specific criteria
- Atypical network
- Regression
- Irregular dots/ globules
- Irregular blotch
- Irregular streaks/ pseudopods
- Shiny white streaks
- Blue/ white veil
- Atypical vessels
Additional criterion for early melanoma in situ
Irregular Hyperpigmented areas
Fast-growing nodular nevi are most common in patients…
Without nevi.
High nevus count confers —— Prognosis in melanoma patients
favorable
In Germany they demonstrated …. Less melanoma death from 100,000 patients screened
1
However in the same study on a long-term follow-up this patient’s had…
1 less regional metastases. 4% versus 13%.
2 left distant metastases. 4% versus 8%
3 required less systemic treatment 12% versus 22%
4 experienced survival benefit, hazard ratio 0.4
