Patients with multiple nevi

Question 1

Atypical nevi. Indicator, precursor or simulator?

Answer 1

Indicator

Question 2

BAP1 1 inactivation syndrome

Answer 2

mutation pap 1 gene
multiple dermal nevi
ocular melanoma
pancreas Ca

Question 3

Typical and atypical nevi may indicate increased melanoma risk

Answer 3

T

Question 4

Can you tell from morphology in which nevus the melanoma will develop

Answer 4

No

Question 5

In Australia, annual risk of melanoma in nevus

Answer 5

1:200 000

Question 6

In Australia annual risk of melanoma on face

Answer 6

1:8000

Question 7

short term monitoring of single lesions

Answer 7

Picky atypical nevi
Any change results in excision - 3/12 months

Question 8

Long term monitoring of multiple lesons

Answer 8

Monitor all nevi
Only significant change results in excision 6-12 monts

Question 9

Non intervention : How many lesions to detect one melanoma

Question 10

Non intervention : how many changed lesion do we need to excise to detect one melanoma?

Question 11

Non intervention : Did we decrease number of excisions

Question 12

intervention : How many lesions to detect one melanoma

Question 13

intervention : how many changed lesion do we need to excise to detect one melanoma?