Rare skin tumours Flashcards

Question

Cutaneous angiosarcoma - associated with lymphedema

Answer 1

occurring years after radiation | occurring after years of lymphedema

Answer 2

Typical colours of vascular tumours - red, purple, blue and white lines in nodular area

Answer 3

0.2-0.45 cases per 100 000 100 times rarer than melanoma increasing incidence recent years

Answer 4

sun exposed - because immune suppressed mainly elderly but not only rapidly enlarging reddish dome shaped nodule

Answer 5

milky red area polymorphous vascular pattern may be arborizing white lines

Answer 6

Wide local excision. Some recommend sentinel bx. Some recommend only wide excision and radiation. role of radiotherapy debated

Answer 7

BCC, SCC, Melanoma

Answer 8

Poor tend to recur after incomplete excision Metastasizes

Answer 9

classified according to adnexal differentiation

Answer 10

follicular sebaceous eccrine apocrine

Answer 11

Associated with complex syndromes

Answer 12

arborizing vessels | blue grey dots or globules

Answer 13

``` desmoplastic trichoepithelioma pilomatricoma Trichilemmona Trichilemmal carcinoma Trichodiscoma ```

Answer 14

``` Usually arises on face or scalp Small nodule Usually present for a long time Ivory-white background colour short vessels - not sharply focussed. ```

Answer 15

Young patients/ children Firm on palpation. Sometimes tender on palpation

Answer 16

``` Irregular white and yellow structures White streaks Reddish homogenous areas Linear vessels Ulceration Blue grey areas ```

Answer 17

Verrucous lesion

Answer 18

keratin masses | perivascular whitish halos

Answer 19

Cowden syndrome

Answer 20

may cause cicatricial alopecia (don't see the hair follicle.)

Answer 21

Wide excision

Answer 22

young patients may be solitary when multiple think about Birt Hogg Dube syndrome usually syndrome is diagnoses before dermatologist sees patient.

Answer 23

whitish globular structures distributed in a cobblestone-like pattern combined with blue-grey nests blurred linear vessels

Answer 24

Congenital nevus | Seb keratosis

Answer 25

``` Eccrine poroma Eccrine porocarcinoma Hidrocystoma Syringomas Syringocystadenoma papilliferum Cyclindroma Spiradenoma ```

Answer 26

Typical arises on feet and palms of hands | Slowly enlarging nodule

Answer 27

Polymorphous vessels with white halo | Peripheral yellowish structures

Answer 28

Can mimic everything - pigmented BCC, pigmented melanoma, amelanotic melanoma

Answer 29

arises on pre-existing benign poroid tumours as reddish ulcerated nodule

Answer 30

Amelanotic tumour Polymorphous vascular pattern - dotted and linear irregular vessels ulceration

Answer 31

predilection for peri-orbital areas | lesions may be found on other areas of face, head and trunk

Answer 32

structureless skin coloured/ yellowish to bluish areas possibly in combination with linear vessels

Answer 33

commonest sweat gland tumour

Answer 34

yellowish/brownish structureless background | possible combined with scarce fine linear vessels

Answer 35

Uncommon clinical condition Multiple yellow/brown firm papule No specific site predilection Young adults

Answer 36

Arises mainly from sebaceous tumours | Nodule with a lot of yellow colour dt keratin masses

Answer 37

yellow colour dt keratin masses pink background linear not in focus vessels

Answer 38

``` Cyclindroma Spiradenoma Trichodiscoma Trichilemmoma Sebaceous tumours Keratoacanthomas ```

Answer 39

overlapping characteristics of BCC linear vessels unfocused and arranged at periphery of the lesion. sometimes yellowish pinkish background and arborizing vessels

Answer 40

``` Multiple skin tumours Developing from skin appendages Spiradenomas Trichoepitheliomas Cylindromas ```

Answer 41

``` solitary painful nodular young adults trunk and upper extremities ```

Answer 42

usually develops as solid lesion (nodule) on the scalp or face of adult females

Answer 43

``` Multiple trichodiscomas Associated with benign and malignant renal neoplasms, Lung cysts Spontaneous pneumothorax ```

Answer 44

``` AKA multiple hamartoma syndrome Young age Trichilemmoma Oral mucosal papillomatosis Acral keratoses Palmoplantar keratoses Associated with malignancy - breast Ca, thyroid Ca, Colon Ca, Renal cell Ca. Usually the dermatologist is last one to see the patient. ```

Answer 45

Phenotypic variant of Lynch syndrome (non polyposis colon cancer syndrome) Autosomal dominant Sebaceous tumours Multiple keratoacanthoma Early onset visceral tumours (Colon and urinary tract)

Answer 46

Sebaceomas Sebaceous adenoma Sebaceous carcinoma

Answer 47

One presentation: Yellowish ovoid nests Arborizing vessels not in focus Alternate presentation: Short dotted and linear vessels at periphery In centre, either keratin mass, or ulceration, or yellowish mass. More resembling keratoacanthoma

Answer 48

SC: unfocussed arborizing vessels over a white to yellow background and few loosely arranged yellow comedo like globules. BCC: In focus arborizing vessels and ulceration.

Answer 49

SA: Central crater, crown vessels, opaque structureless, white centre, blood crusts. SH: Crown vessels, page structureless, white/yellow centre. SCC: Keratotic material. White circles.

Answer 50

very rare very aggressive typical in immunosuppressed patient Upper eyelid is common site

Answer 51

wide local excision

Answer 52

white reddish background dotted vessels ulceration yellowish hyperkeratotic material

Answer 53

1. Collect and document cases 2. Excise rapidly evolving nodular lesions with atypical vascular pattern in Dermoscopy. High chance of malignancy. 3. Collaborate with pathologist 4. Multidisciplinary approach to management. 5. Look for associated syndromes. 6. Genetic counselling.