Scope of Micro Pathogen

Question 1

Bacterial Pathogen ?

Answer 1

Legionella pneumophila

Question 2

Legionella pneumophila gram reaction

Answer 2

Gram-negative rod

Question 3

Legionella pneumophila lives?

Answer 3

Freshwater

Question 4

Legionella pneumophila causes ?

Answer 4

Legionaires disease

Question 5

Legionella pneumophila transmission

Answer 5

Airbrone

Question 6

Legionella pneumophila pathogenesis

Answer 6

• inhaled-> lungs
• engulfed by alveolar marcophages
• multiply inside alveolar macrophages
• alveolar marcophages destroyed-> legionella pneumophila released-> infect more alveolar macrophages

Question 7

Legionnaires disease signs

Answer 7

Fever, cough, SOB, muscle aches

Question 8

Legionnaires Disease Dx

Answer 8

Culture and Antigen Identification

Question 9

Legionnaires disease Tx

Answer 9

Erythromycin

Azithromycin

Question 10

Fungi Microbe pathogen

Answer 10

Coccidiodes immitis

Question 11

Coccidioides immitis causes ?

Answer 11

Coccidiomycosis “valley fever”

Question 12

Coccidioides immitis transmission ?

Answer 12

Airborne

Question 13

Coccidioides immitis pathogenesis

Answer 13

Inhaled-> infects lungs

Question 14

Coccidioidomycosis signs

Answer 14

Fever, cough, SOB, Chest pain

Question 15

Coccidioidomycosis Dx

Answer 15

Detection of Coccidioides immits antigens or antibodies

Question 16

Coccidioidomycosis Tx

Answer 16

Fluconazole

Question 17

Protozoa microbe pathogen

Answer 17

Naegleria fowleri

Question 18

Naegleria fowleri lives?

Answer 18

Freshwater

Question 19

Naegleria fowleri causes?

Answer 19

Primary amebic meningoencephalitis

Question 20

Naegleria fowleri transmission

Answer 20

Waterborne up nose infects tissue and destroys brain

Question 21

Naegleria fowleri Pathogenesis

Answer 21

Nasal mucosa-> brain -> destorys brain tissue

Question 22

Primary ambeic meningoencephalitis sign

Answer 22

Early: headache, fever, nausea, vomiting

Later: stiff neck, confusion, lack of attn, loss of balance, seizures, hallucinations

Question 23

Primary ambeic meningoenchephalitis Dx:

Answer 23

CSF sample -> microscopy

Question 24

Primary amebic meningoencephalitis fatality rate

Answer 24

High

Question 25

Primary Amebic Meningoencephalitis Tx:

Answer 25

Therapeutic hypothermia & miltefosine

Question 26

Multicellular Animal Parasite Microbe pathogen

Answer 26

Helminths (hookworm)

Question 27

Hookworm etiological agents

Answer 27

- Nector americanus | - Ancylostoma duodenale

Question 28

Hookworm transmission

Answer 28

Larvae burrow through skin

Question 29

Life cycle of nector americanus/ ancylostoma duodenale

Answer 29

1. Eggs in soil -> hatch into larvae 2. Larvae burrow into human skin> bloodstream> heart> lungs 3. In lungs, larvae penetrate alveoli > bronchial tree> throat> swallowed

Question 30

Life cycle of necator americanus/ Ancylostoma duodenale

Answer 30

4. Larvae reach intestine and mature into adult hookworms 5. Adult hookworms attach to intestinal wall 6. Eggs shed in feces

Question 31

Hookworm sign

Answer 31

Iteching, cough, abd. Pain, diarrhea, anemia

Question 32

Hookworm Dx

Answer 32

Microscopic identification of Nector americanus/ ancylostoma eggs in feces

Question 33

Hookworm tx

Answer 33

Mebendazole/ albendazole

Question 34

Micorbe virus pathogen

Answer 34

Hantavirus

Question 35

Hantavirus causes

Answer 35

Hantavirus pulmonary syndrome

Question 36

Most common hantavirus

Answer 36

Sin nombre virus

Question 37

Hantavirus transmission

Answer 37

Airborne

Question 38

Hantavirus reservoir

Answer 38

Rodents

Question 39

Hantavirus transmission

Answer 39

Shed in rodent urine > inhaled

Question 40

Hantavirus pathogenesis

Answer 40

- inhaled > endothelial cells in lungs | - hantavirus replicates in endothelial cells> damage > vasodilation and increased blood vessel permeability

Question 41

Hantavirus pulmonary syndrome sign

Answer 41

Early: fatigue, fever, muscle aches Late: pulmonary edmea, cough, SOB, shock

Question 42

Hantavirus pulmonary syndrome Dx

Answer 42

Detection of hantavirus antigens and antibodies

Question 43

Hangavirus pulmonary syndrome Tx

Answer 43

Mechinical respiration | Ribavirin

Question 44

Microbe prion

Answer 44

Proteinaceous infection particles | Induce abnormal folding of proteins in brain> brain damage