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Microbiology > Scope of Micro Pathogen > Flashcards

Scope of Micro Pathogen Flashcards

1
Q

Bacterial Pathogen ?

A

Legionella pneumophila

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2
Q

Legionella pneumophila gram reaction

A

Gram-negative rod

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3
Q

Legionella pneumophila lives?

A

Freshwater

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4
Q

Legionella pneumophila causes ?

A

Legionaires disease

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5
Q

Legionella pneumophila transmission

A

Airbrone

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6
Q

Legionella pneumophila pathogenesis

A
  • inhaled-> lungs
  • engulfed by alveolar marcophages
  • multiply inside alveolar macrophages
  • alveolar marcophages destroyed-> legionella pneumophila released-> infect more alveolar macrophages
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7
Q

Legionnaires disease signs

A

Fever, cough, SOB, muscle aches

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8
Q

Legionnaires Disease Dx

A

Culture and Antigen Identification

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9
Q

Legionnaires disease Tx

A

Erythromycin

Azithromycin

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10
Q

Fungi Microbe pathogen

A

Coccidiodes immitis

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11
Q

Coccidioides immitis causes ?

A

Coccidiomycosis “valley fever”

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12
Q

Coccidioides immitis transmission ?

A

Airborne

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13
Q

Coccidioides immitis pathogenesis

A

Inhaled-> infects lungs

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14
Q

Coccidioidomycosis signs

A

Fever, cough, SOB, Chest pain

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15
Q

Coccidioidomycosis Dx

A

Detection of Coccidioides immits antigens or antibodies

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16
Q

Coccidioidomycosis Tx

A

Fluconazole

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17
Q

Protozoa microbe pathogen

A

Naegleria fowleri

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18
Q

Naegleria fowleri lives?

A

Freshwater

19
Q

Naegleria fowleri causes?

A

Primary amebic meningoencephalitis

20
Q

Naegleria fowleri transmission

A

Waterborne up nose infects tissue and destroys brain

21
Q

Naegleria fowleri Pathogenesis

A

Nasal mucosa-> brain -> destorys brain tissue

22
Q

Primary ambeic meningoencephalitis sign

A

Early: headache, fever, nausea, vomiting

Later: stiff neck, confusion, lack of attn, loss of balance, seizures, hallucinations

23
Q

Primary ambeic meningoenchephalitis Dx:

A

CSF sample -> microscopy

24
Q

Primary amebic meningoencephalitis fatality rate

25
Q

Primary Amebic Meningoencephalitis Tx:

A

Therapeutic hypothermia & miltefosine

26
Q

Multicellular Animal Parasite Microbe pathogen

A

Helminths (hookworm)

27
Q

Hookworm etiological agents

A
  • Nector americanus

- Ancylostoma duodenale

28
Q

Hookworm transmission

A

Larvae burrow through skin

29
Q

Life cycle of nector americanus/ ancylostoma duodenale

A
  1. Eggs in soil -> hatch into larvae
  2. Larvae burrow into human skin> bloodstream> heart> lungs
  3. In lungs, larvae penetrate alveoli > bronchial tree> throat> swallowed
30
Q

Life cycle of necator americanus/ Ancylostoma duodenale

A
  1. Larvae reach intestine and mature into adult hookworms
  2. Adult hookworms attach to intestinal wall
  3. Eggs shed in feces
31
Q

Hookworm sign

A

Iteching, cough, abd. Pain, diarrhea, anemia

32
Q

Hookworm Dx

A

Microscopic identification of Nector americanus/ ancylostoma eggs in feces

33
Q

Hookworm tx

A

Mebendazole/ albendazole

34
Q

Micorbe virus pathogen

A

Hantavirus

35
Q

Hantavirus causes

A

Hantavirus pulmonary syndrome

36
Q

Most common hantavirus

A

Sin nombre virus

37
Q

Hantavirus transmission

38
Q

Hantavirus reservoir

39
Q

Hantavirus transmission

A

Shed in rodent urine > inhaled

40
Q

Hantavirus pathogenesis

A
  • inhaled > endothelial cells in lungs

- hantavirus replicates in endothelial cells> damage > vasodilation and increased blood vessel permeability

41
Q

Hantavirus pulmonary syndrome sign

A

Early: fatigue, fever, muscle aches
Late: pulmonary edmea, cough, SOB, shock

42
Q

Hantavirus pulmonary syndrome Dx

A

Detection of hantavirus antigens and antibodies

43
Q

Hangavirus pulmonary syndrome Tx

A

Mechinical respiration

Ribavirin

44
Q

Microbe prion

A

Proteinaceous infection particles

Induce abnormal folding of proteins in brain> brain damage

Microbiology (7 decks)

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