History Of micro Patho

Question 1

Yersinia pestis is pathogen for

Answer 1

The plague

Question 2

Yersinia pestis gram stain

Answer 2

Gram (-) rod

Question 3

Yersinia pestis causes

Answer 3

Palgue

Question 4

Yesrinia pestis transmission rodent

Answer 4

rodent

Most common; rats, mice, squirrels

Question 5

Yersinia pestis vector

Answer 5

Flea

Takes blood meal from infected rodent > injects Yersinia oestis into human

Question 6

Yersinia pestis pathogenesis

Answer 6

• engulf by white blood cells
• survive inside of wbc and multiply
• WBC bursts > yersinia pestis released

Question 7

What are the three forms of plague

Answer 7

Bubonic, speticemic, pneumonic

Question 8

Bubonic plague transmission

Answer 8

Bite from infected flea

Question 9

Bubonic plague yesrinia pestis transmission

Answer 9

Travels through lymphatic system > lymph nodes

Question 10

Bubonic plague multiply

Answer 10

Lymph nodes > buboes

Question 11

Bubonic plague signs

Answer 11

Weakness, fever buboes

Question 12

Bubonic plague mortaloty rate

Answer 12

50-70%

Question 13

Septicemic plague transmission

Answer 13

Contact with contaminted fluid/tissue

Can develop from bubonic plague

Question 14

Septicemic plague signs

Answer 14

Weakness, fever
Bleeding into skin
Gangrene

Question 15

Selticemic plague mortality rate

Answer 15

80-90%

Question 16

Pneumonic plague transmission

Answer 16

Droplet

Can develop from septicemic plague

Question 17

Pneumonic plague signs

Answer 17

Weakness fever, SOB, Coughing

Question 18

Pneumonic plague mortality rate

Answer 18

Almost 100%

Question 19

Plague Dx

Answer 19

Culture

Question 20

Plague Tx

Answer 20

Gentamicin, fluroquinolones

Question 21

Smallpox

Answer 21

Scabs on body

Killed many

Question 22

Variolation

Answer 22

Means of inducing immunity to smallpox

Question 23

Variola virus vauses

Answer 23

Smallpx

Question 24

Variola virus transmission

Answer 24

Droplet and fomites

Question 25

Variola Virus Pathogenesis

Answer 25

Infects lymph nodes -bloodwork -skin (Variola virus grows in epidermal layer of skin )

Question 26

Stages of smallpox ; incubation period

Answer 26

Signs; none | Notcontagious

Question 27

Smallpox intial symptoms

Answer 27

Signs: fever , body aches | Sometimes contagious

Question 28

Smallpox: early rash signs

Answer 28

Small spots in mouth-> sores that break open Rash in skin Most contagious

Question 29

Smallpox: pustular rash and scabs signs

Answer 29

Pustles and scabs | Contagious

Question 30

Stages of smallpox scans off

Answer 30

Scabda fall off ; contagious

Question 31

Smallpx no scabs

Answer 31

Not contagious

Question 32

Smallpox dx

Answer 32

Detection of Variola Virus nucleic acids

Question 33

Smallpox Tx

Answer 33

Vaccine within 2 days of exposure