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Microbiology > History Of micro Patho > Flashcards

History Of micro Patho Flashcards

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Biology 101 flashcards
1
Q

Yersinia pestis is pathogen for

A

The plague

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2
Q

Yersinia pestis gram stain

A

Gram (-) rod

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3
Q

Yersinia pestis causes

A

Palgue

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4
Q

Yesrinia pestis transmission rodent

A

rodent

Most common; rats, mice, squirrels

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5
Q

Yersinia pestis vector

A

Flea

Takes blood meal from infected rodent > injects Yersinia oestis into human

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6
Q

Yersinia pestis pathogenesis

A
  • engulf by white blood cells
  • survive inside of wbc and multiply
  • WBC bursts > yersinia pestis released
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7
Q

What are the three forms of plague

A

Bubonic, speticemic, pneumonic

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8
Q

Bubonic plague transmission

A

Bite from infected flea

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9
Q

Bubonic plague yesrinia pestis transmission

A

Travels through lymphatic system > lymph nodes

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10
Q

Bubonic plague multiply

A

Lymph nodes > buboes

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11
Q

Bubonic plague signs

A

Weakness, fever buboes

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12
Q

Bubonic plague mortaloty rate

A

50-70%

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13
Q

Septicemic plague transmission

A

Contact with contaminted fluid/tissue

Can develop from bubonic plague

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14
Q

Septicemic plague signs

A

Weakness, fever
Bleeding into skin
Gangrene

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15
Q

Selticemic plague mortality rate

A

80-90%

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16
Q

Pneumonic plague transmission

A

Droplet

Can develop from septicemic plague

17
Q

Pneumonic plague signs

A

Weakness fever, SOB, Coughing

18
Q

Pneumonic plague mortality rate

A

Almost 100%

19
Q

Plague Dx

A

Culture

20
Q

Plague Tx

A

Gentamicin, fluroquinolones

21
Q

Smallpox

A

Scabs on body

Killed many

22
Q

Variolation

A

Means of inducing immunity to smallpox

23
Q

Variola virus vauses

A

Smallpx

24
Q

Variola virus transmission

A

Droplet and fomites

25
Q

Variola Virus Pathogenesis

A

Infects lymph nodes
-bloodwork
-skin
(Variola virus grows in epidermal layer of skin )

26
Q

Stages of smallpox ; incubation period

A

Signs; none

Notcontagious

27
Q

Smallpox intial symptoms

A

Signs: fever , body aches

Sometimes contagious

28
Q

Smallpox: early rash signs

A

Small spots in mouth-> sores that break open
Rash in skin
Most contagious

29
Q

Smallpox: pustular rash and scabs signs

A

Pustles and scabs

Contagious

30
Q

Stages of smallpox scans off

A

Scabda fall off ; contagious

31
Q

Smallpx no scabs

A

Not contagious

32
Q

Smallpox dx

A

Detection of Variola Virus nucleic acids

33
Q

Smallpox Tx

A

Vaccine within 2 days of exposure

Microbiology (7 decks)

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