Class. of microorganisms Patho Flashcards

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1
Q

What is an example of a strain ?

A

Escherichia coli O157:H7

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2
Q

Escherichia coli O157:H7 gram stain ?

A

Gram neg. rod

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3
Q

Escherichia coli O157:H7 found in?

A

Guts in animals

Main reservoir: cattle

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4
Q

Escherichia coli O157:H7 causes

A

Foodborne illness

Hemo Uremic syndrome

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5
Q

Escherichia coli O157:H7 transmission

A

Fecal-oral route

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6
Q

Escherichia coli O157:H7 pathogenesis

A

-ingested >stomach
- acid-resistant
- colonizes intestines ( attaches to microvilli of intestinal cells )
Releases shigalike toxin
( disrupts protein syenthesis in intestinal cells>cell death )

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7
Q

Escherichia coli foodborne illness sign

A

Severe abd. Cramps
Blody diarrhea
Vomitting

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8
Q

Escherichia coli foodborne dx

A

Stool culture

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9
Q

Escherichia coli tx

A

Supportive

-no antibiotics

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10
Q

Escherichia coli & Hemolytic uremic syndrom

A
  • sigalike toxin crosses from intestine into bloodstream
  • shigalike toxin binds to red blood cells > destruction of RBCs
  • Damaged RBCs reach kidneys and clog filtering system
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11
Q

Hemolytic Uremic Syndrome signs

A

Anemia
Low platlet count
Kidney failure

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12
Q

Hemolytic uremic syndrome dx

A

Blood tests

Stool culture

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13
Q

Hemolytic uremic syndrome tx

A

Rbc/ platelet infusions

Dialysis

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14
Q

Influenza Virus causes

A

Flu

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15
Q

Influenza virus season

A

December - march

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16
Q

Influenza virus RNA virus

A

8 segments of rna

17
Q

Influenza viral protein (H)

A

Hemagglutinin; binds to sialic acid on host cells

18
Q

Influenza viral proteins (N) :

A

Neuraminidase ; helps virus exit cell

19
Q

Influenza A infects

A

Humans & animals

20
Q

Infleunza A divides

A

Into strains based on H and N
18 different H proteins
11different N proteins

21
Q

Influenza B infects

A

Humans only

22
Q

Influenza C infects

A

Kids, huamns and pigs

23
Q

Infulenza D infects

A

Cattle

24
Q

Influenza transmission

A

Droplet
Fomites
Occur before symtpoms

25
Q

Infleunza Pathogensis

A
  • Hemagglutinin binds to sialic acid receptors on epithelial cells if respiratory tract
  • influenza virus reolicates inside repirstory epithelial cells

- influenza virus is released from cell and spreads other respiratory eoithelial cells a

26
Q

Influenza Dx

A

Nucleic acid identification

27
Q

Influenza tx:

A

Supportive, antivirals available by Rx

28
Q

Infleunza Prevetion

A

Hand washing

Flu shot