Scleroderma Flashcards
1
Q
What antibodies are involved in scleroderma?
A
Anti-scl-70
Anti-centromere
2
Q
What are the 2 types of scleroderma?
A
Limited
Diffuse
3
Q
Which antibody causes limited scleroderma?
A
Anti-centromere
4
Q
Which antibody causes diffuse scleroderma?
A
Anti-scl-70
5
Q
What is deposited in scleroderma?
A
Calcium –> calcinosis
6
Q
What is the syndrome of scleroderma
A
CREST syndrome
7
Q
What does CREST syndrome stand for?
A
Calcinosis Raynauds Eosophagitis Sclerodactyl Telangiectasia
8
Q
What is sclerdactyl?
A
Swelling of the fingers
9
Q
What are the symptoms of limited (anti-scl-70) scleroderma?
A
Heartburn
Raynauds
Sclerodactyl
10
Q
What are the symptoms of diffuse scleroderma?
A
Internal organs affected Joint pain Itchy rash Weight loss Fatigue
11
Q
What type of rash is seen in diffuse scleroderma?
A
Morphodiscoloured itchy patches
12
Q
Complication of diffuse?
A
Interstitial lung disease
Renal crisis
13
Q
Treatment?
A
Immune suppression
