Polymyalgia Rheumatica Flashcards
What is it?
Inflammatory condition in elderly women
What is it related to?
GCA
What is the typical presentation?
70 y/o woman presents with sudden onset of severe shoulder pain and pelvic girdle that is worse in the morning. She can’t get out of her chair.
Why can’t the patient get out of a chair?
PMR causes proximal muscle weakness
Systemic symptoms?
Malaise Anaemia Fever Weight loss Depression
ARTHRALGIA
Investigations?
Bloods
What is diagnostic on blood findings?
ESR >50
What is diagnostic treatment wise?
If they get better on steroids it was PMR not MM
1st line treatment?
Prednisolone w/ bone prophylaxis
What should happen to the ESR with prednisolone treatment?
Should normalise in 4 weeks
2nd line treatment?
Methotrexate
3rd line treatment?
Tocilizumab
What is tocilizumab?
IL-6 receptor MAB