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Conditions: Rheumatology > Juvenile Idiopathic Arthritis > Flashcards

Juvenile Idiopathic Arthritis Flashcards

1
Q

Aetiology of JIA?

A

Autoimmune

- Unknown but strong genetic link

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2
Q

Age range?

A

<16 years

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3
Q

General symptoms?

A 
Fatigue
Malaise
Arthritis
Disability
- Blindness
- Refusal to walk
Pleural issues

TENOSYNOVITIS

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4
Q

DDx?

A

Acute septic arthritis (MUST BE RULED OUT)

Osteomyelitis

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5
Q

Gender difference?

A

Mostly > girls

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6
Q

What are the 2 broad subtypes?

A

Pauciarticular < or equal to 4 joints affected

>4 joints affected

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7
Q

What is found in type 1 pauciarticular?

A

ANA +ve in most cases

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8
Q

What age range is type 1 pauciarticular?

A

1-3 years

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9
Q

What joints are typically affected in type 1?

A

Any but RARELY HIP

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10
Q

What telltale symptom may be present in type 1?

A

Chronic uveitis

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11
Q

What can chronic uveitis lead to?

A

Blindness

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12
Q

What is the name given to type 2 pauciarticular JIA?

A

Enthesitis related

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13
Q

What gene may be affected in type 2 pauciarticular JIA?

A

HLA-B27

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14
Q

Who is most likely affected in type 2 pauciarticular JIA?

A

Boys

7-8 yrs

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15
Q

Why is it called enthesitis related?

A

Can cause enthesitis of the achilles tendon

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16
Q

What is type 3 pauciarticular JIA related to?

A

Psoriasitic arthritis

  • Usually also has a +ve FH of psoriasis
  • Patient may develop symptoms particularly nail pitting
17
Q

What hand signs can be seen in type 3 PA JIA?

A

Dactylitis

18
Q

What joints are affected in type 3 PA JIA?

A

Asymmetrical upper limb

19
Q

What are the 2 types of >4 joints affected JIA?

A

RF +ve

RF -ve

20
Q

What symptom may be present in RF -ve that shouldn’t be present in any others?

A

Symmetrical

Low fecer

21
Q

What is RF +ve JIA pretty much?

A

Rheumatoid arthritis <16

22
Q

What is STILLs disease?

A

Any number of joints with JIA with systemic disease

  • Spiking fever (very high)
  • Shock symptoms

Rash
Generalised lymphadenopathy
HSM
Serositis

23
Q

What is the type of rash in STILLs disease?

A

Salmon pink eruption

24
Q

What can be caused by serositis?

A

Pericarditis

Rarely pleurisy

25
Q

What must be ruled out in JIA?

A

Sepsis!!!!!”!!”!£!”£!”$!£%FDFGwgWEGR`

26
Q

Tests?

A

Bloods

  • ESR raised
  • FBC
  • RF
  • ANA
  • ASO

USS

27
Q

Why is an FBC done?

A

Rule out malignancy

28
Q

What is ASO?

A

Anti-streptolysin

Can be raised in JIA without evidence of recent strep infection

29
Q

1st line treatment in polyarthritis?

30
Q

2nd line treatment in mono-JIA?

A

I.A. Steroid injections

31
Q

2nd line typical treatment?

32
Q

Who MUST all children be referred to with JIA?

33
Q

What are the anti-TNF drugs that can be used in DMARD therapy?

A

Infliximab

Etanercept

Conditions: Rheumatology (26 decks)

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