Schultz-Oct 4

Question 1

How many elements does RNAPIII Type 1 promoter have?

Answer 1

3

Question 2

How many elements does RNAPIII Type 2 promoter have?

Answer 2

2

Question 3

How many elements does RNAPIII Type 3 promoter have?

Answer 3

3

Question 4

How many subunits does RNAPIII have?

Answer 4

17

Question 5

What is TFIIIB made of?

Answer 5

TBP, Brf1, B”

Question 6

What is CK2?

Answer 6

protein kinase

Question 7

What are the components of RNAPIII translation machinery? (x3) (type 2 promoter)

Answer 7

TFIIIC, TFIIIB, CK2

Question 8

What sequences does TFIIIC need to recognize?

Answer 8

DNA sequences in the A and B blocks

Question 9

interaction between B” and Brf1 help with what?

Answer 9

RNAPIII recruitment

Question 10

In RNAPIII type 1 promoter, what sequence does TFIIIA recognize?

Answer 10

DNA sequences in C block

Question 11

In RNAPIII type III promoter, what brings TFs to PSE?

Answer 11

SNAPc

Question 12

What is Maf1?

Answer 12

Universal repressor of RNAPIII transcription

Question 13

Mutation in what gene causes Treacher Collins Syndrome?

Answer 13

POLR1D

Question 14

What proteins does the POL1RD gene encode?

Answer 14

RPAC2