Schultz-Oct 11 Flashcards
1
Q
Access of the transcriptional machinery to DNA in chromatin is regulated by? (x2)
A
- chromatin modifying enzymes
- chromatin remodelling enzymes
2
Q
Which end of histones is usually modified?
A
amino (N)
3
Q
Writer
A
put marks on
4
Q
Eraser
A
removes/reverses modifications
5
Q
Reader
A
recognizes marks
6
Q
3 types of histone modification
A
- acetylation
- methylation
- phosphorylation
7
Q
2 types of HATs
A
- GNATs
- MYST acetyltransferases
8
Q
What in GNAT binds acetylated histones?
A
BrD
9
Q
What in MYST binds methyalted histones?
A
CHD
