Schizophrenia Medications EXAM II 2020 Flashcards
atypical anti-psychotic that may cause agranulocytosis, suppress bone marrow formation. Cause decrease in granulocytes,
-WBC must be at least 3.5 or greater prior to administration. May decrease seizure threshold and cause seizures
Clozapine
atypical anti-psychotic that has strong ACH effects, high sedation, may increase weght, cause metabolic syndrome, highly sedative.
-best to administer at bedtime.
Quetiapine
atypical anti-psychotic that increase levels of D2 receptors & block 5HT. EPS may develop when dose exceeds 6-8 mg. Highly sedative. Usually given for aggressive/agitative behavior.
-Can be given at bedtime to enhance sleep. Assess fall risk
Long active injectable available
Risperidone
atypical anti-psychotic that 5HT/NE reuptake. Prolonged QT intervals (dysrhythmias). IM injection is available. Does not cause weight gain.
-can cause sedation and dizziness. encourage to take with food to increase absorption.
Ziprasidone
atypical anti-psychotic Like clozapine without agranulocytosis. Sedative, Available in oral disintegrating tabs.
-very sedative, so recommended to give at bedtime. Requires monitoring for metabolic syndrome
Olanzapine
atypical anti-psychotic that does not cause weight gain. Stabilizes DA receptors. mildly sedative.
-can be given during the daytime hours
aripiprazole