Schizophrenia: Drug Treatmeant (Biological treatment)

Question 1

What are the different types of generations of drugs created to treat psychosis

Answer 1

1st generation, 2nd generation and 3rd generation.

Question 2

What is an example of a first generation drug

Answer 2

Chlorpromazine

Question 3

What type of medication is chlopromazine, and what does it do

Answer 3

Dopomine antagonist, it reduces positive symptoms

Question 4

How does it reduce positive symptoms

Answer 4

It blocks dopomine receptors in the post-synaptic neuron without activating these receptors.

Question 5

What is the reported problems of using this drug

Answer 5

• 40% of people reported no effect of this drug
• people still experience negative symptoms

Question 6

What is a side effect of this drug

Answer 6

• tireness
• weight gain
• constipation
• stiff and slow movement of face muscles

Question 7

What is an example of a second generation drug

Answer 7

Clozapine

Question 8

What does clozapine do

Answer 8

Blocks dopamine receptors in the post synaptic nueron as well as serotonin and glutamate receptors

Question 9

What is a big side effect in taking this drug?

Answer 9

Patients can develop a fatal condition which is why this drug isnt perscribed as often.

Question 10

What are the precautions of the patients that do take this drug

Answer 10

They must take regular blood tests to make sure they aren’t developing the condition.

Question 11

What symptoms doeas clozapine target

Answer 11

positive and negative symptoms

Question 12

Whats the reported relief rate of clozapine for treatment resistant clients who take them

Answer 12

60%

Question 13

Evaluation

Answer 13

Evaluation

Question 14

What is a strength of drug treatments

Answer 14

Research evidence from Ying Zhoa et al showed good evidence for using drug treatments

Question 15

What research did Ying Zhoa undergo?

Answer 15

Meta-analysis of 56 randomsied controled trails comparing 18 antipsychotics. Over 10,000 people were involved

Question 16

What did Ying Zhao find

Answer 16

17 of the 18 antipsychotics has significantly lower relapse rates than the placebo.

Question 17

Why is this a strength

Answer 17

Shows that drug treatment is a cheaper and still effective alternative for treatment than therapy.

Question 18

What is a weakness of the research done on drug treatments

Answer 18

Most the research conducted on antispychotics is done on animals, so you cannot generalise much of it to humans.

Question 19

Why can’t you generlise animal research for humans

Answer 19

Although some research shows symptoms are removed, animals cannot show how side effects would interfere with everyday life

Question 20

What is a strength of the application drug treatments had

Answer 20

De-intitutionalisation of patients with schizophrenia

Question 21

What does that basically mean

Answer 21

Instead of schizophrenia sufferes having to spend their days in a care hospital, they could live a regular life in the community as they were now able to suppres symptoms with drugs.