Schizophrenia Flashcards

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1
Q

Schizophrenia

A

a psychotic disorder involving serious impairment of attention, thought, language, emotion, and behaviour
•Coined by Eugen Bleuler
•Affects 1% of people in Canada

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2
Q

What does a diagnosis of schizophrenia require?

A

Evidence that a person misinterprets reality, and exhibits disordered attention, thought or perception

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3
Q

Delusions

A

false beliefs, often involving themes of persecution or grandeur, that are sustained in the face of evidence that normally would be sufficient to destroy them

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4
Q

What are two types of dilution?

A

Dilution of persecution

Dilution of grandeur

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5
Q

Hallucinations

A

false perceptions that have a compelling sense of reality (typically voices speaking to the patient)

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6
Q

What are 3 types of affects related to schizophrenia?

A
  • Blunted affect: manifesting less sadness, joy and anger than most people
  • Flat affect: showing almost no emotion at all
  • Inappropriate affect: wrong emotions for the situation
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7
Q

What are the 4 subtypes of schizophrenia in the old DSM-IV-TR ?

A

Paranoid
Disorganized
Catatonic
Undifferentiated

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8
Q

What is typical for patients in catatonic state (not just for schizophrenia) ?

A

Striking motor disturbances,
• From muscular rigidity to random or repetitive movements

Catatonics can alternate between stuporous states in which they seem oblivious to reality and agitated excitement during which they can be dangerous to others

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9
Q

What is waxy flexibility?

A

Catatonics in a stuporous state may exhibit a waxy flexibility in which their limbs can be moulded by another person into grotesque positions that they will then maintain for hours

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10
Q

Type 1 schizophrenia

A

subtype of schizophrenia characterized by a predominance of positive symptoms
•subtype of schizophrenia characterized by a predominance of positive symptoms

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11
Q

Positive symptoms

A
  • Better prognosis for recovery

* schizophrenic symptoms such as delusions, hallucinations, and disordered speech and thinking

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12
Q

Type 2 Schizophrenia

A

subtype of schizophrenia characterized by negative symptoms

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13
Q

Negative symptoms

A
  • associated with a long history of poor functioning prior to hospitalization and poor outcome following treatment
  • schizophrenic symptoms that reflect a lack of normal reactions, such as emotions or social behaviours
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14
Q

Structural differences (in brain) are more common in what type of schizophrenia?

A

Negative-Symptom

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15
Q

Brain atrophy

A

A general loss of deterioration of neurons in the cerebral cortex and limbic systems, together with enlarged ventricles (cavities that contain cerebrospinal fluid)

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16
Q

What does the neurodegenerative hypothesis say?

A

Destruction of neural tissue can cause schizophrenia

17
Q

What brain abnormalities are associated with schizophrenia?

A
  • Brain atrophy
  • Abnormalities in the thalamus which sends bad information to the cerebral cortex accounts for disordered attention and perception
18
Q

Dopamine Hypothesis

A

view that the symptoms of schizophrenia (particularly positive) are produced by overactivity of the dopamine system in areas of the brain that regulate emotional expression, motivated behaviour, and cognitive functioning
•People diagnosed with schizophrenia have more dopamine receptors on neuron membranes, and the receptors are overreactive

19
Q

How do antipsychotic drugs work?

A

Reduce dopamine -produces synaptic activity

20
Q

What are some biochemical factors to schizophrenia?

A

Dopamine overactivity

Deficiency of neural input from cortical areas play a role

21
Q

Regression

A

a psychoanalytic defence mechanism in which a person retreats back to an earlier stage of development in response to stress

22
Q

The Social Causation Hypothesis

A

The higher prevalence of schizophrenia to the higher levels of stress that low-income people experience, particularly within urban environments

23
Q

The Social Drift Hypothesis

A

As people develop schizophrenia, their personal and occupational functioning deteriorates, so that they drift down the socioeconomic ladder into poverty and migrate to low-cost urban environments

24
Q

Where is the likelihood of recovery of schizophrenia greater, developed or developing countries? Why?

A

Developing countries

•Stronger community orientation and greater social support extended to disturbed people in developing countries

25
Q

What is the psychoanalyst perspective of schizophrenia?
What is the psychodynamic?
Cognitive?

A

Psychoanalyst: Regression

Psychodynamic: Focusing on the interpersonal withdrawal, view the disorder as a retreat from an interpersonal world that has become too stressful to deal with

Cognitive: A defect in the attentional mechanism that filters out irrelevant stimuli. The stimulus overload produces distractibility, thought disorganization and the sense of being overwhelmed by disconnected thoughts and ideas

26
Q

What did PET scans reveal at times when schizophrenics were hearing voices?

A

The auditory and visual areas of the cortex were highly active, but there was no activity in the prefrontal cortex (prefrontal function to distinguish reality from fantasy)

27
Q

Expressed emotion

A

a family interaction pattern involving criticism, hostility, and overinvolvement that is associated with relapse when formerly hospitalized schizophrenic patients return home

28
Q

What is a theory of family dynamics on biological vulnerability?

A

Biological vulnerability factor must be present if stressful familial events are to cause their damage