SBA Paper 1 Flashcards

1
Q

Role of Desmosomes

A

Attach cells via the intermediate filaments

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2
Q

What is an adherens junction?

A

Joins an actin bundle in one cell to a similar bundle in its neighbouring cell

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3
Q

What are the role of hemidesmosomes?

A

Anchor intermediate filaments in cells to the basal lamina

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4
Q

What are the role of tight junctions?

A

Seal neighbouring cells together to prevent leakage of molecules

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5
Q

What are the role of gap junctions?

A

Allow the passage of small, water soluble ions and molecules

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6
Q

Haematoxylin and Eosin

A

Stain nuclei purple and cytoplasm pink

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7
Q

Periodic Acid Schiff

A

Stains brush borders and hexose sugars dark pink

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8
Q

Van Gieson

A

Stains collagen pink and muscle yellow

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9
Q

Alcian Blue

A

Stains mucins blue

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10
Q

Incidence

A

The number of new cases within a specified time period divided by the population size initially at risk

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11
Q

Neutrophils are elevated in…

A

bacterial infections

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12
Q

Eosinophils are elevated in…

A

parasitic infections

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13
Q

Basophils are involved in…

A

inflammatory reactions

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14
Q

Cytotoxic T-lymphocytes are elevated in…

A

acute and chronic infections

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15
Q

Adrenaline acting on α2 receptors causes…

A

Vasodilation of the peripheral nervous system

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16
Q

Adrenaline acting on β2 receptors causes…

A

increased contractility and heart rate (increased CO)

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17
Q

The activation of baroreceptors would cause…

A

Decreased ADH (Less water retained, BP decreases)

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18
Q

Which part of the anatomical dead space has got the largest area?

A

Trachea

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19
Q

Where can simple columnar epithelium be found?

A

Lines the GI system

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20
Q

Where can stratified squamous epithelium be found?

A

Usually located in areas where frictional forces occur

eg. Skin, oesophagus, vagina, vocal cords

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21
Q

Where can simple cuboidal epithelium be found?

A

Secretory / Excretory surfaces

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22
Q

Where can simple squamous epithelium be found?

A

PERMEABLE - found where transport of small molecules occurs

eg. lungs, capilleries, alveoli

23
Q

Where can stratified columnar epithelium be found?

A

Secretion and protection.

Pharynx, anus, uterus

24
Q

Airway smooth muscle constriction is stimulated by by acetylcholine acting on…

A

M3 subtype of muscarinic receptors

25
Q

Somatostatin is a GI hormone which has inhibitory effect on…

A

Secretion of every hormone

26
Q

CCK is the major inhibitor of…

A

gastric emptying

27
Q

What is the function of lipoprotein lipase

A

Hydrolyses triglycerides to produce fatty acids and glycerol

28
Q

Where is the main site of exocrine secretion in the pancreas?

A

Pancreatic acini

29
Q

Where is the main site of endocrine secretion in the pancreas?

A

Islets of Langerhans

30
Q

Which areas of the pancreas does the ventral bud form?

A

Uncinate process and head. Main pancreatic duct

31
Q

In a distribution of data, if the median is greater than the mean, what is it described as?

A

Negative skew

32
Q

What is the equation for odds?

A

Odds = number of events / number of non-events

33
Q

What are Renshaw Cells

A

Inhibitory interneurons located in the ventral cord

34
Q

What does the urogenital sinus develop into?

A

External genitalia

Lower 1/3 vagina, labia minora and majora, clitoris

35
Q

What do the Mullerian ducts develop into?

A

Uterine tubes, uterus, cervix, upper 2/3 of vagina

36
Q

The urogenital organs are developed from which layer of germ cells?

A

Intermediate mesoderm

37
Q

T8 is where…

A

the IVC passes through the diaphragm

38
Q

T10 is where…

A

the oseophagus passes through the diaphragm

39
Q

T12 is where…

A

the aorta passes through the diaphragm

40
Q

L1 is the level at which what artery branches off the aorta?

A

The superior mesenteric artery

41
Q

L2 is the level at which what artery branches off the aorta?

A

The renal arteries

42
Q

L3 is the level at which what artery branches off the aorta?

A

The inferior mesenteric artery

43
Q

The urethral folds develop into the…

A

labia minora and corpus spongiosum

44
Q

The tubercle develops into the…

A

clitoris and glans penis

45
Q

The labioscrotal folds develop into the…

A

labia majora and scrotum and ventral penis

46
Q

What is the order of the histological layers of the epidermis from exterior to interior

A

Corneum, Lucidum , Granulosum, Spinosum, Basale

Come Let’s Get Some Beers

47
Q

In a healthy person, the oncotic pressure in Bowman’s space should be…

A

low or 0. The kidney does not filter proteins, therefore they should not be found in the Bowman’s space.

48
Q

In embryology, the kidneys develop…

A

low in the pelvis and ascend

49
Q

What does the bladder develop from?

A

The urogenital sinus

50
Q

In what week of development does the kidney become functional?

A

Week 12

51
Q

Which nerve is commonly damaged by anterior shoulder dislocation or fracture of the humerus?

A

Axillary

52
Q

What is Trendelenburg’s sign

A

Pelvis drop on the opposite side to weakness of gluteus minimus and medius

Left side gluteus medius and minimus weakness causes right side pelvic drop

53
Q

What are the big 5 CAM in the NHS?

A

Acupuncture, Chiropractics, Herbal Medicine, Homeopathy, Osteopathy
ACHHO