MedSoc SBAs Flashcards
Some inherited diseases, such as hypertrophic cardiomyopathy can be caused by mutations in different genes. What is this called?
Locus heterogenecity
Would a high HCO3 concentration in the blood be associated with ketoacidosis?
No
What is the rate limiting enzyme in the TCA (Krebs’) cycle
Isocitrate dehydrogenase
Renin is released…
secondary to a decrease in renal perfusion
Where is ADH synthesised?
The hypothalamus - it is released from the posterior pituitary
How is cortisol transported around the body?
Bound to plasma proteins
Severe pulmonary hypertension often happens as a result of…
right sided heart failure
A tumour of the what can be symptomless until it starts impeding on neighbouring structures?
The nasopharynx
What is the dermatome for the umbilicus?
T10
What is McBurney’s point?
The point 1/3 of the way from the ASIS to the umbilicus. It is the point where the most pain is elicited in acute appendicitis.
What is the secretion of the parotid glands?
Serous - contains amylase
From which week of pregnancy is surfactant detectable?
Week 24
At what level does the spinal cord end?
L2 (L1/L2)
Vasopressin (ADH) predominantly acts upon what parts of the kidney?
The distal convoluted tubule and collecting ducts
What does the zona fasciculata of the adrenal glands secrete?
Cortisol
What vein drains the adrenal glands?
The suprarenal vein
What structure allows communication between the greater and lesser omental sac?
The foramen of Winslow
In the coagulation cascade, what activates fibrinogen?
Factor IIa
What is the identifying characteristic of a neutrophil?
Multilobed nucleus
What is the identifying characteristic of a basophil?
Bilobed nucleus
What is the identifying characteristic of a eosinophil?
Bilobed, lozenge shaped nucleus
Where is Vitamin D 25 hydroxylase found and what does it produce?
Liver
Produces calcidiol from cholecalciferol
Where is Vitamin D 1 hydroxylase found and what does it produce?
Kidney
Produces calcitriol from calcidiol