Salivary Gland Pathology Flashcards
What would hint at a malignant salivary gland pathology?
young and painful
What is sialolithiasis?
salivary gland stones
What is a common infection of the salivary glands?
paramyxovirus - risk of secondary meningitis
What is the most common site for tumours?
parotid
tumours in smaller glands are more likely to be malignant
What is the most common salivary gland tumour?
pleomorphic adenoma
Describe a pleomorphic adenoma?
slow growing
indolent tumours
in parotid gland
What populations are affected by pleomorphic adenomas?
females
4-6th decade
Can pleomorphic adenomas become malignant?
yes if longstanding
What is the treatment for pleomorphic adenomas?
tricky to excise but can reocurr
What is a Warthins tumour?
bilateral and multicentric tumour
rare outwith the parotid
What are the risk factors of Warthins tumours?
males >50
smoking
What is the most common worldwide malignant salivary gland tumours?
mucoepidermoid carcinoma
What is the most common UK malignant salivary gland tumours?
adenoid cystic carcinoma
Describe a mucoepidermoid carcinoma?
majority in the parotid gland
wide age range
can be classified into low risk (>90% 5 year survival)
or high risk (<60% 5 year survival)
Describe an adenoid cystic carcinoma?
most common malignant tumour of the palate
35% 5 year survival
frequent perinural invasion
What is a common symptom of adenoid cystic carcinoma?
pain
loss of function
What populations are most commonly affected by adenoid cystic carcinoma?
over 40years
How are parotid tumours viewed?
CT scan
What is the gold standard investigation for salivary gland tumours?
Ultrasound - can do FNA guided biopsy
shows the type and lobulation
What is the order from first, to last investigations are done for salivary gland tumours?
USS -> FNA -> CT -> MRI -> PET
How do salivary gland tumours present?
facial weakness
difficulty swallowing
What is a non epithelial salivary gland tumour?
lymphoma
What are red flags for salivary gland tumours?
solid nodule irregular or microlobulated margins internal vascularity interval increase in size micro calcification marked hypoechogenicity metastatic lymphadenopathy